Drug targets for urinary and faecal incontinence and anal fissures

Student thesis: Doctoral Thesis

Abstract

The aim of this PhD project was to increase our understanding of the pharmacology of the urethra and the anorectum. Specifically, the intent was to elucidate the pharmacology of the smooth muscle of the urethra and the anorectum; to establish the influence of the urothelial lining on urethral contraction; to investigate the mediators and neurotransmitters involved in the regulation of these tissues and to characterise the intracellular signalling pathways involved in contraction and relaxation.
Date of Award11 Feb 2017
Original languageEnglish
SupervisorDonna Sellers (Supervisor) & Russ Chess-Williams (Supervisor)

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