Was the study big enough? Two "café" rules

Paul Glasziou*, Helen Doll

*Corresponding author for this work

Research output: Contribution to journalEditorialResearch

2 Citations (Scopus)


When reading an article, we often wonder whether the study was large enough. If a study does not find a statistically significant effect (e.g., at P < 0.05), it may be because the study was too small or because there actually is no true effect. You should check whether the CIs show that the data are consistent with a clinically important effect, even though the effect was not “statistically significant.”
Original languageEnglish
Pages (from-to)A8-9
JournalACP Journal Club
Issue number3
Publication statusPublished - 2007
Externally publishedYes


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