Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family

Michael J. Soares, Teresa N Faria, Gary P Hamlin, Xing Jian Lu, Santanu Deb

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Abstract

Normal growth and maturation of a specialized extraembryonic structure, the placenta, are essential for the establishment and maintenance of pregnancy. The placenta acts as the interface between maternal and embryonic compartments, developing in parallel with the embryo and facilitating the acquisition of maternal resources required for embryonic and fetal development. This essential responsibility of the placenta is accomplished in a number of important ways, including (i) regulation of the transport of nutrients and wastes, (ii) an immunologic role in preventing fetal rejection, and (iii) an endocrine/communication/signaling role between fetal and maternal compartments. Consequently, understanding the control of placental development is fundamental to an appreciation of the initiation and maintenance of pregnancy and various abnormalities associated with altered growth and development. The cells responsible for these diverse functions of the placenta are trophoblast cells.
Original languageEnglish
Title of host publicationTrophoblast Cells
Subtitle of host publicationPathways for Maternal-Embryonic Communication
EditorsMichael J. Soares, Stuart Handwerger, Frank Talamantes
Place of PublicationNew York
PublisherSpringer
Chapter4
Pages45-67
Number of pages23
ISBN (Electronic)978-1-4612-2718-2
ISBN (Print)978-1-4612-7641-8
DOIs
Publication statusPublished - 1993
Externally publishedYes

Publication series

NameProceedings in the Serono Sympsia, USA Series
PublisherSpringer-Verlag

Fingerprint

Trophoblasts
Prolactin
Placenta
Cell Differentiation
Pregnancy Maintenance
Mothers
Embryonic and Fetal Development
Placentation
Growth and Development
Embryonic Structures
Food
Growth

Cite this

Soares, M. J., Faria, T. N., Hamlin, G. P., Lu, X. J., & Deb, S. (1993). Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family. In M. J. Soares, S. Handwerger, & F. Talamantes (Eds.), Trophoblast Cells: Pathways for Maternal-Embryonic Communication (pp. 45-67). (Proceedings in the Serono Sympsia, USA Series). New York: Springer. https://doi.org/10.1007/978-1-4612-2718-2_4
Soares, Michael J. ; Faria, Teresa N ; Hamlin, Gary P ; Lu, Xing Jian ; Deb, Santanu. / Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family. Trophoblast Cells: Pathways for Maternal-Embryonic Communication. editor / Michael J. Soares ; Stuart Handwerger ; Frank Talamantes. New York : Springer, 1993. pp. 45-67 (Proceedings in the Serono Sympsia, USA Series).
@inbook{cb761a5c5c1d476ab181a928cabbbf7d,
title = "Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family",
abstract = "Normal growth and maturation of a specialized extraembryonic structure, the placenta, are essential for the establishment and maintenance of pregnancy. The placenta acts as the interface between maternal and embryonic compartments, developing in parallel with the embryo and facilitating the acquisition of maternal resources required for embryonic and fetal development. This essential responsibility of the placenta is accomplished in a number of important ways, including (i) regulation of the transport of nutrients and wastes, (ii) an immunologic role in preventing fetal rejection, and (iii) an endocrine/communication/signaling role between fetal and maternal compartments. Consequently, understanding the control of placental development is fundamental to an appreciation of the initiation and maintenance of pregnancy and various abnormalities associated with altered growth and development. The cells responsible for these diverse functions of the placenta are trophoblast cells.",
author = "Soares, {Michael J.} and Faria, {Teresa N} and Hamlin, {Gary P} and Lu, {Xing Jian} and Santanu Deb",
year = "1993",
doi = "10.1007/978-1-4612-2718-2_4",
language = "English",
isbn = "978-1-4612-7641-8",
series = "Proceedings in the Serono Sympsia, USA Series",
publisher = "Springer",
pages = "45--67",
editor = "Soares, {Michael J.} and Stuart Handwerger and Frank Talamantes",
booktitle = "Trophoblast Cells",
address = "Germany",

}

Soares, MJ, Faria, TN, Hamlin, GP, Lu, XJ & Deb, S 1993, Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family. in MJ Soares, S Handwerger & F Talamantes (eds), Trophoblast Cells: Pathways for Maternal-Embryonic Communication. Proceedings in the Serono Sympsia, USA Series, Springer, New York, pp. 45-67. https://doi.org/10.1007/978-1-4612-2718-2_4

Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family. / Soares, Michael J.; Faria, Teresa N; Hamlin, Gary P; Lu, Xing Jian; Deb, Santanu.

Trophoblast Cells: Pathways for Maternal-Embryonic Communication. ed. / Michael J. Soares; Stuart Handwerger; Frank Talamantes. New York : Springer, 1993. p. 45-67 (Proceedings in the Serono Sympsia, USA Series).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

TY - CHAP

T1 - Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family

AU - Soares, Michael J.

AU - Faria, Teresa N

AU - Hamlin, Gary P

AU - Lu, Xing Jian

AU - Deb, Santanu

PY - 1993

Y1 - 1993

N2 - Normal growth and maturation of a specialized extraembryonic structure, the placenta, are essential for the establishment and maintenance of pregnancy. The placenta acts as the interface between maternal and embryonic compartments, developing in parallel with the embryo and facilitating the acquisition of maternal resources required for embryonic and fetal development. This essential responsibility of the placenta is accomplished in a number of important ways, including (i) regulation of the transport of nutrients and wastes, (ii) an immunologic role in preventing fetal rejection, and (iii) an endocrine/communication/signaling role between fetal and maternal compartments. Consequently, understanding the control of placental development is fundamental to an appreciation of the initiation and maintenance of pregnancy and various abnormalities associated with altered growth and development. The cells responsible for these diverse functions of the placenta are trophoblast cells.

AB - Normal growth and maturation of a specialized extraembryonic structure, the placenta, are essential for the establishment and maintenance of pregnancy. The placenta acts as the interface between maternal and embryonic compartments, developing in parallel with the embryo and facilitating the acquisition of maternal resources required for embryonic and fetal development. This essential responsibility of the placenta is accomplished in a number of important ways, including (i) regulation of the transport of nutrients and wastes, (ii) an immunologic role in preventing fetal rejection, and (iii) an endocrine/communication/signaling role between fetal and maternal compartments. Consequently, understanding the control of placental development is fundamental to an appreciation of the initiation and maintenance of pregnancy and various abnormalities associated with altered growth and development. The cells responsible for these diverse functions of the placenta are trophoblast cells.

U2 - 10.1007/978-1-4612-2718-2_4

DO - 10.1007/978-1-4612-2718-2_4

M3 - Chapter

SN - 978-1-4612-7641-8

T3 - Proceedings in the Serono Sympsia, USA Series

SP - 45

EP - 67

BT - Trophoblast Cells

A2 - Soares, Michael J.

A2 - Handwerger, Stuart

A2 - Talamantes, Frank

PB - Springer

CY - New York

ER -

Soares MJ, Faria TN, Hamlin GP, Lu XJ, Deb S. Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family. In Soares MJ, Handwerger S, Talamantes F, editors, Trophoblast Cells: Pathways for Maternal-Embryonic Communication. New York: Springer. 1993. p. 45-67. (Proceedings in the Serono Sympsia, USA Series). https://doi.org/10.1007/978-1-4612-2718-2_4