TY - JOUR
T1 - Treating chronic fatigue syndrome
T2 - A study into the scientific evidence for pharmacological treatments
AU - Kreijkamp-Kaspers, Sanne
AU - Brenu, Ekua Weba
AU - Marshall-Gradisnik, Sonya
AU - Staines, Don R
AU - Van Driel, Mieke L.
PY - 2011/11
Y1 - 2011/11
N2 - Background: Chronic fatigue syndrome, or myalgic encephalomyelitis (CFS), is a severe disabling condition. Patients with CFS usually trial many different medicines, both conventional and complementary. An overview of the pharmacological treatments used by CFS patients and the available evidence underpinning the use of these treatments would be of great value to both patients and their healthcare providers. Methods: Ninety-four CFS patients recruited into an Australian study investigating immunological biomarkers filled out a questionnaire assessing the medicines they were taking. Evidence from randomised clinical trials was sought in biomedical databases. Results: The 94 CFS patients used 474 different medicines and supplements. The most commonly used medicines were antidepressants, analgesics, sedatives, and B vitamins. We identified 20 randomised controlled trials studying these medicines in CFS patients. Conclusion: While conventional and complementary medicines are widely used by CFS patients, the evidence for effectiveness in CFS is very limited.
AB - Background: Chronic fatigue syndrome, or myalgic encephalomyelitis (CFS), is a severe disabling condition. Patients with CFS usually trial many different medicines, both conventional and complementary. An overview of the pharmacological treatments used by CFS patients and the available evidence underpinning the use of these treatments would be of great value to both patients and their healthcare providers. Methods: Ninety-four CFS patients recruited into an Australian study investigating immunological biomarkers filled out a questionnaire assessing the medicines they were taking. Evidence from randomised clinical trials was sought in biomedical databases. Results: The 94 CFS patients used 474 different medicines and supplements. The most commonly used medicines were antidepressants, analgesics, sedatives, and B vitamins. We identified 20 randomised controlled trials studying these medicines in CFS patients. Conclusion: While conventional and complementary medicines are widely used by CFS patients, the evidence for effectiveness in CFS is very limited.
UR - http://www.scopus.com/inward/record.url?scp=84856016949&partnerID=8YFLogxK
M3 - Article
C2 - 22059223
AN - SCOPUS:84856016949
SN - 2208-7958
VL - 40
SP - 907
EP - 912
JO - Australian Family Physician
JF - Australian Family Physician
IS - 11
ER -