Transdiagnostic Group Cognitive-Behavioral Therapy: A Review

Peter J. Norton; Joanne E. Brooker; Michael Di Mattia; Rose Anne Misajon; Richard Moulding; Alexandra E. Paton

doi:10.1016/j.ypsc.2025.02.003

Transdiagnostic Group Cognitive-Behavioral Therapy: A Review

Peter J. Norton^*
, Joanne E. Brooker
, Michael Di Mattia
, Rose Anne Misajon
, Richard Moulding
, Alexandra E. Paton

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Research › peer-review

1 Citation (Scopus)

Abstract

Key points:
•Data from 5 clinical trials support the clinical efficacy of transdiagnostic cognitive behavioral therapy (tCBT), including equivalent efficacy to diagnosis-specific CBT.
•Data from one large pragmatic randomized controlled trial established treatment effectiveness of tCBT in real-world conditions.
•Multiple secondary analyses show positive effects of tCBT on comorbid mental health diagnoses.
•Two health economic studies, from the societal and health care systems perspectives respectively, show high probability of cost-effectiveness of tCBT.
•Data from multiple secondary analyses consistently demonstrated strong treatment acceptability among patients.

Original language	English
Pages (from-to)	37-45
Number of pages	9
Journal	Advances in Psychiatry and Behavioral Health
Volume	5
Issue number	1
DOIs	https://doi.org/10.1016/j.ypsc.2025.02.003
Publication status	Published - Sept 2025
Externally published	Yes

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SDG 3 Good Health and Well-being

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title = "Transdiagnostic Group Cognitive-Behavioral Therapy: A Review",

abstract = "Key points: •Data from 5 clinical trials support the clinical efficacy of transdiagnostic cognitive behavioral therapy (tCBT), including equivalent efficacy to diagnosis-specific CBT. •Data from one large pragmatic randomized controlled trial established treatment effectiveness of tCBT in real-world conditions. •Multiple secondary analyses show positive effects of tCBT on comorbid mental health diagnoses. •Two health economic studies, from the societal and health care systems perspectives respectively, show high probability of cost-effectiveness of tCBT. •Data from multiple secondary analyses consistently demonstrated strong treatment acceptability among patients.",

author = "Norton, \{Peter J.\} and Brooker, \{Joanne E.\} and \{Di Mattia\}, Michael and Misajon, \{Rose Anne\} and Richard Moulding and Paton, \{Alexandra E.\}",

year = "2025",

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doi = "10.1016/j.ypsc.2025.02.003",

language = "English",

volume = "5",

pages = "37--45",

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AU - Norton, Peter J.

AU - Brooker, Joanne E.

AU - Di Mattia, Michael

AU - Misajon, Rose Anne

AU - Moulding, Richard

AU - Paton, Alexandra E.

PY - 2025/9

Y1 - 2025/9

N2 - Key points: •Data from 5 clinical trials support the clinical efficacy of transdiagnostic cognitive behavioral therapy (tCBT), including equivalent efficacy to diagnosis-specific CBT. •Data from one large pragmatic randomized controlled trial established treatment effectiveness of tCBT in real-world conditions. •Multiple secondary analyses show positive effects of tCBT on comorbid mental health diagnoses. •Two health economic studies, from the societal and health care systems perspectives respectively, show high probability of cost-effectiveness of tCBT. •Data from multiple secondary analyses consistently demonstrated strong treatment acceptability among patients.

AB - Key points: •Data from 5 clinical trials support the clinical efficacy of transdiagnostic cognitive behavioral therapy (tCBT), including equivalent efficacy to diagnosis-specific CBT. •Data from one large pragmatic randomized controlled trial established treatment effectiveness of tCBT in real-world conditions. •Multiple secondary analyses show positive effects of tCBT on comorbid mental health diagnoses. •Two health economic studies, from the societal and health care systems perspectives respectively, show high probability of cost-effectiveness of tCBT. •Data from multiple secondary analyses consistently demonstrated strong treatment acceptability among patients.

UR - https://www.scopus.com/pages/publications/105001977499

U2 - 10.1016/j.ypsc.2025.02.003

DO - 10.1016/j.ypsc.2025.02.003

M3 - Review article

AN - SCOPUS:105001977499

SN - 2667-3835

VL - 5

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JO - Advances in Psychiatry and Behavioral Health

JF - Advances in Psychiatry and Behavioral Health

IS - 1

ER -

Transdiagnostic Group Cognitive-Behavioral Therapy: A Review

Abstract

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