ntroduction. Isolated strips of the urothelium and lamina propria (U&LP) develop spontaneous contractions which can be modulated through activation of the muscarinic and adrenergic receptor systems. However, the mechanisms underlying this activity are unknown and it is not clear how the apical urothelial layer influences the overall activity. Aims. This study aims to identify if the pacemakers in the isolated tissue samples can be inhibited through the blockade of gap junctions, c-Kit inhibition, or disruption to the urothelium.
|Number of pages||1|
|Publication status||Published - 2011|
|Event||ASCEPT-AuPS-HBPRCA Joint Meeting Program - Perth, Australia|
Duration: 4 Dec 2011 → 9 Dec 2011
|Conference||ASCEPT-AuPS-HBPRCA Joint Meeting Program|
|Period||4/12/11 → 9/12/11|
Moro, C., Sellers, D. J., & Chess-Williams, R. (2011). The Lamina Propria is responsible for the General of the Spontaneous Contractile Activity of the Urothelium/Lamina Propria. 66-66. Abstract from ASCEPT-AuPS-HBPRCA Joint Meeting Program , Perth, Australia. http://ascept2011.eproceedings.com.au/papers/p103.pdf