The influence of dopamine on automatic and controlled semantic activation in Parkinson's disease

Wendy L. Arnott, David A. Copland, Helen J. Chenery, Bruce E. Murdoch, Peter A. Silburn, Anthony J. Angwin

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Abstract

Two semantic priming tasks, designed to isolate automatic and controlled semantic activation, were utilized to investigate the impact of dopamine depletion on semantic processing in Parkinson's disease (PD). Seven people with PD (tested whilst on and off levodopa medication) and seven healthy adults participated in the study. The healthy adult participants demonstrated intact automatic and controlled semantic activation. Aberrant controlled semantic activation was observed in the PD group on levodopa; however, automatic semantic activation was still evident. In contrast, automatic semantic activation was not evident in the PD group off levodopa. These results further clarify the impact of PD on semantic processing, demonstrating that dopamine depletion can cause disturbances in both automatic and controlled semantic activation.

Original languageEnglish
Article number157072
JournalParkinson's Disease
DOIs
Publication statusPublished - 2011
Externally publishedYes

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Semantics
Parkinson Disease
Dopamine
Levodopa
Healthy Volunteers

Cite this

Arnott, W. L., Copland, D. A., Chenery, H. J., Murdoch, B. E., Silburn, P. A., & Angwin, A. J. (2011). The influence of dopamine on automatic and controlled semantic activation in Parkinson's disease. Parkinson's Disease, [157072]. https://doi.org/10.4061/2011/157072
Arnott, Wendy L. ; Copland, David A. ; Chenery, Helen J. ; Murdoch, Bruce E. ; Silburn, Peter A. ; Angwin, Anthony J. / The influence of dopamine on automatic and controlled semantic activation in Parkinson's disease. In: Parkinson's Disease. 2011.
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The influence of dopamine on automatic and controlled semantic activation in Parkinson's disease. / Arnott, Wendy L.; Copland, David A.; Chenery, Helen J.; Murdoch, Bruce E.; Silburn, Peter A.; Angwin, Anthony J.

In: Parkinson's Disease, 2011.

Research output: Contribution to journalArticleResearchpeer-review

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