The influence of dopamine on automatic and controlled semantic activation in Parkinson's disease

Wendy L. Arnott, David A. Copland, Helen J. Chenery, Bruce E. Murdoch, Peter A. Silburn, Anthony J. Angwin*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Abstract

Two semantic priming tasks, designed to isolate automatic and controlled semantic activation, were utilized to investigate the impact of dopamine depletion on semantic processing in Parkinson's disease (PD). Seven people with PD (tested whilst on and off levodopa medication) and seven healthy adults participated in the study. The healthy adult participants demonstrated intact automatic and controlled semantic activation. Aberrant controlled semantic activation was observed in the PD group on levodopa; however, automatic semantic activation was still evident. In contrast, automatic semantic activation was not evident in the PD group off levodopa. These results further clarify the impact of PD on semantic processing, demonstrating that dopamine depletion can cause disturbances in both automatic and controlled semantic activation.

Original languageEnglish
Article number157072
JournalParkinson's Disease
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint Dive into the research topics of 'The influence of dopamine on automatic and controlled semantic activation in Parkinson's disease'. Together they form a unique fingerprint.

Cite this