The connection between PARP14 and SARS-CoV-2

Amanda L Tauber; Stephanie S Schweiker; Stephan M Levonis

doi:10.4155/fmc-2023-0013

The connection between PARP14 and SARS-CoV-2

Amanda L Tauber
, Stephanie S Schweiker
, Stephan M Levonis^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

Abstract

In our 2021 article, we explored the overlap between the SARS-CoV-2 infe ction and the activity of the poly (ADP-ribose) polymerase family member 14 (PARP14)[1]. We identified three key actions including, PARP14 counterbalancing the pro-inflammatory cytokines of SARS-CoV-2 cytokine storm, PARP14’s role in the interferon (IFN) response to aid in clearing the virus and how this may be combatted by the de-mono (ADP-ribosyl) ation (MARylating) activity of the coronavirus macrodomain.

Original language	English
Pages (from-to)	225-227
Number of pages	3
Journal	Future Medicinal Chemistry
Volume	15
Issue number	3
DOIs	https://doi.org/10.4155/fmc-2023-0013
Publication status	Published - 1 Feb 2023

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10.4155/fmc-2023-0013

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abstract = "In our 2021 article, we explored the overlap between the SARS-CoV-2 infe ction and the activity of the poly (ADP-ribose) polymerase family member 14 (PARP14)[1]. We identified three key actions including, PARP14 counterbalancing the pro-inflammatory cytokines of SARS-CoV-2 cytokine storm, PARP14{\textquoteright}s role in the interferon (IFN) response to aid in clearing the virus and how this may be combatted by the de-mono (ADP-ribosyl) ation (MARylating) activity of the coronavirus macrodomain.",

author = "Tauber, \{Amanda L\} and Schweiker, \{Stephanie S\} and Levonis, \{Stephan M\}",

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N2 - In our 2021 article, we explored the overlap between the SARS-CoV-2 infe ction and the activity of the poly (ADP-ribose) polymerase family member 14 (PARP14)[1]. We identified three key actions including, PARP14 counterbalancing the pro-inflammatory cytokines of SARS-CoV-2 cytokine storm, PARP14’s role in the interferon (IFN) response to aid in clearing the virus and how this may be combatted by the de-mono (ADP-ribosyl) ation (MARylating) activity of the coronavirus macrodomain.

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The connection between PARP14 and SARS-CoV-2

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The potential association between PARP14 and SARS-CoV-2 infection (COVID-19)

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The connection between PARP14 and SARS-CoV-2

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The potential association between PARP14 and SARS-CoV-2 infection (COVID-19)

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