The benefits and limitations of methadone: A comparison to other opioid replacement treatments

Yousif S. Mahdi, Ahmed A. Moustafa

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Abstract

The key aim of this chapter is to review the use of methadone as the most widely applied synthetic opioid used to treat chronic addiction. The implications of the treatment are reviewed, specifically its inability to adequately completely eradicate addiction symptoms. Our review of literature shows that while methadone has some benefits, it also has many limitations including the potential to reinforce addiction as well as withdrawal. This review also aims to bring attention to lesser-known alternative treatments to opiate addiction, including Levo-alpha-acetylmethadol, buprenorphine, and naltrexone. While these medications have overcome some of the limitations of methadone, they also carry other side effects, which we also discuss in this article.

Original languageEnglish
Title of host publicationCognitive, Clinical, and Neural Aspects of Drug Addiction
PublisherElsevier - Mosby
Chapter13
Pages267-287
Number of pages21
ISBN (Electronic)9780128169797
ISBN (Print)9780128169803
DOIs
Publication statusPublished - 1 Jan 2020
Externally publishedYes

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