Targeted Therapies and Nanomedicine: Precision at the Molecular Level

Melanoma is an aggressive skin cancer type with high incidence and mortality rates globally. Despite advances in Next Generation Sequencing (NGS), effective treatment for melanoma remains a challenge. The role of nanomedicine in cancer research, including melanoma, is an ongoing collaborative effort to improve targeted therapies and overall patient outcomes. Similar to any other treatment approach, there are existing barriers to the clinical applications of nanomedicine as a cancer treatment. This chapter focuses on molecular mechanisms involved in melanoma-targeted therapies, the current nanomedicine trends in enhancing melanoma treatments, and the convergence of nanomedicine, targeted therapies, and immunotherapies as enhanced melanoma treatment modalities. Furthermore, research areas that focus on addressing the limitations of nanomedicine have been identified. Nanomedicine and targeted therapies are a promising frontier in advancing melanoma precision medicine.