Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies

Melissa M Lane; Nikolaj Travica; Elizabeth Gamage; Skye Marshall; Gina L Trakman; Claire Young; Scott B Teasdale; Thusharika Dissanayaka; Samantha L Dawson; Rebecca Orr; Felice N Jacka; Adrienne O'Neil; Mark Lawrence; Phillip Baker; Casey M Rebholz; Shutong Du; Wolfgang Marx

doi:10.1146/annurev-nutr-062322-020650

Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies

Melissa M Lane, Nikolaj Travica, Elizabeth Gamage, Skye Marshall, Gina L Trakman, Claire Young, Scott B Teasdale, Thusharika Dissanayaka, Samantha L Dawson, Rebecca Orr, Felice N Jacka, Adrienne O'Neil, Mark Lawrence, Phillip Baker, Casey M Rebholz, Shutong Du, Wolfgang Marx

Faculty of Health Sciences & Medicine

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Abstract

Our aim was to conduct an umbrella review of evidence from meta-analyses of observational studies investigating the link between sugar-sweetened beverage consumption and human health outcomes. Using predefined evidence classification criteria, we evaluated evidence from 47 meta-analyses encompassing 22,055,269 individuals. Overall, 79% of these analyses indicated direct associations between greater sugar-sweetened beverage consumption and higher risks of adverse health outcomes. Convincing evidence (class I) supported direct associations between sugar-sweetened beverage consumption and risks of depression, cardiovascular disease, nephrolithiasis, type 2 diabetes mellitus, and higher uric acid concentrations. Highly suggestive evidence (class II) supported associations with risks of nonalcoholic fatty liver disease and dental caries. Out of the remaining 40 meta-analyses, 29 were graded as suggestive or weak in the strength of evidence (classes III and IV), and 11 showed no evidence (class V). These findings inform and provide support for population-based and public health strategies aimed at reducing sugary drink consumption for improved health.

Original language	English
Pages (from-to)	383-404
Number of pages	22
Journal	Annual Review of Nutrition
Volume	44
Issue number	1
DOIs	https://doi.org/10.1146/annurev-nutr-062322-020650
Publication status	Published - Aug 2024

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10.1146/annurev-nutr-062322-020650Licence: CC BY

Sugar-Sweetened Beverages and Adverse Human Health Outcomes An Umbrella Review of Meta-Analyses of Observational StudiesFinal published version, 307 KBLicence: CC BY

Public health nutrition research
Reidlinger, D., Cox, G., Marshall, S., MacKenzie-Shalders, K., Patterson, P., Campbell, K., Van Herwerden, L., Utter, J., Mayr, H., Van der Meij, B., Kelly, J., Maugeri, B., Marx, W. & Tang, X.
1/01/14 → 31/01/29
Project: Research

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Lane, M. M., Travica, N., Gamage, E., Marshall, S., Trakman, G. L., Young, C., Teasdale, S. B., Dissanayaka, T., Dawson, S. L., Orr, R., Jacka, F. N., O'Neil, A., Lawrence, M., Baker, P., Rebholz, C. M., Du, S., & Marx, W. (2024). Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies. Annual Review of Nutrition, 44(1), 383-404. https://doi.org/10.1146/annurev-nutr-062322-020650

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title = "Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies",

abstract = "Our aim was to conduct an umbrella review of evidence from meta-analyses of observational studies investigating the link between sugar-sweetened beverage consumption and human health outcomes. Using predefined evidence classification criteria, we evaluated evidence from 47 meta-analyses encompassing 22,055,269 individuals. Overall, 79% of these analyses indicated direct associations between greater sugar-sweetened beverage consumption and higher risks of adverse health outcomes. Convincing evidence (class I) supported direct associations between sugar-sweetened beverage consumption and risks of depression, cardiovascular disease, nephrolithiasis, type 2 diabetes mellitus, and higher uric acid concentrations. Highly suggestive evidence (class II) supported associations with risks of nonalcoholic fatty liver disease and dental caries. Out of the remaining 40 meta-analyses, 29 were graded as suggestive or weak in the strength of evidence (classes III and IV), and 11 showed no evidence (class V). These findings inform and provide support for population-based and public health strategies aimed at reducing sugary drink consumption for improved health.",

author = "Lane, {Melissa M} and Nikolaj Travica and Elizabeth Gamage and Skye Marshall and Trakman, {Gina L} and Claire Young and Teasdale, {Scott B} and Thusharika Dissanayaka and Dawson, {Samantha L} and Rebecca Orr and Jacka, {Felice N} and Adrienne O'Neil and Mark Lawrence and Phillip Baker and Rebholz, {Casey M} and Shutong Du and Wolfgang Marx",

year = "2024",

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doi = "10.1146/annurev-nutr-062322-020650",

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Lane, MM, Travica, N, Gamage, E, Marshall, S, Trakman, GL, Young, C, Teasdale, SB, Dissanayaka, T, Dawson, SL, Orr, R, Jacka, FN, O'Neil, A, Lawrence, M, Baker, P, Rebholz, CM, Du, S & Marx, W 2024, 'Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies', Annual Review of Nutrition, vol. 44, no. 1, pp. 383-404. https://doi.org/10.1146/annurev-nutr-062322-020650

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T1 - Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies

AU - Lane, Melissa M

AU - Travica, Nikolaj

AU - Gamage, Elizabeth

AU - Marshall, Skye

AU - Trakman, Gina L

AU - Young, Claire

AU - Teasdale, Scott B

AU - Dissanayaka, Thusharika

AU - Dawson, Samantha L

AU - Orr, Rebecca

AU - Jacka, Felice N

AU - O'Neil, Adrienne

AU - Lawrence, Mark

AU - Baker, Phillip

AU - Rebholz, Casey M

AU - Du, Shutong

AU - Marx, Wolfgang

PY - 2024/8

Y1 - 2024/8

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JF - Annual Review of Nutrition

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Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies

Abstract

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