Role of nutrition impact symptoms in predicting nutritional status and clinical outcome in hemodialysis patients: A potential screening tool

Katrina L Campbell, Judith D Bauer, Aya Ikehiro, David W. Johnson

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Abstract

OBJECTIVE: This study aims to establish the utility of the Nutrition Impact Symptoms (NIS), a part of the Patient-Generated Subjective Global Assessment (PG-SGA) as a nutritional screening tool in patients receiving hemodialysis (HD). DESIGN: This was a prospective observational study. SETTING: The study took place in a single public tertiary in-center dialysis facility in Australia. SUBJECTS: Patients included 213 individuals receiving maintenance HD for at least 3 months who were older than 18 years of age (mean age, 58.9 ± 16.3 years; 55.4% [n = 118] male patients). MAIN OUTCOME MEASURE: Malnutrition, which was classified by the Subjective Global Assessment rating (SGA, B or C) and the nutrition-related clinical outcome (decline in weight [>5%], SGA, reduction in serum albumin [>5 g/L]), or 12-month mortality. RESULTS: Patients assessed as malnourished totaled 23.5% (n = 50). Total PG-SGA and NIS scores showed a comparable ability to predict malnutrition (area under the curve, 0.93 [95% confidence interval {CI}, 0.90-0.97] and 0.86 [95% CI, 0.80-0.93], respectively). NIS (score >=2) was independently related to poor nutrition-related clinical outcome (odds ratio [OR], 3.03; 95% CI, 1.47-6.20) and mortality (OR, 1.11; 95% CI, 1.03-1.20) adjusted for age, dialysis vintage, serum albumin level, and comorbidities. CONCLUSIONS: NIS score is a promising nutritional screening tool for the identification of patients receiving hemodialysis who are at risk of malnutrition and poor clinical outcome. Further research is required to investigate the reliability and utility of this tool in a larger population group.
Original languageEnglish
Pages (from-to)302-307
Number of pages6
JournalJournal of Renal Nutrition
Volume23
Issue number4
DOIs
Publication statusPublished - 1 Jul 2013
Externally publishedYes

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Nutritional Status
Renal Dialysis
Malnutrition
Confidence Intervals
Serum Albumin
Dialysis
Odds Ratio
Nutrition Assessment
Mortality
Population Groups
Area Under Curve
Observational Studies
Comorbidity
Maintenance
Prospective Studies
Weights and Measures
Research

Cite this

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title = "Role of nutrition impact symptoms in predicting nutritional status and clinical outcome in hemodialysis patients: A potential screening tool",
abstract = "OBJECTIVE: This study aims to establish the utility of the Nutrition Impact Symptoms (NIS), a part of the Patient-Generated Subjective Global Assessment (PG-SGA) as a nutritional screening tool in patients receiving hemodialysis (HD). DESIGN: This was a prospective observational study. SETTING: The study took place in a single public tertiary in-center dialysis facility in Australia. SUBJECTS: Patients included 213 individuals receiving maintenance HD for at least 3 months who were older than 18 years of age (mean age, 58.9 ± 16.3 years; 55.4{\%} [n = 118] male patients). MAIN OUTCOME MEASURE: Malnutrition, which was classified by the Subjective Global Assessment rating (SGA, B or C) and the nutrition-related clinical outcome (decline in weight [>5{\%}], SGA, reduction in serum albumin [>5 g/L]), or 12-month mortality. RESULTS: Patients assessed as malnourished totaled 23.5{\%} (n = 50). Total PG-SGA and NIS scores showed a comparable ability to predict malnutrition (area under the curve, 0.93 [95{\%} confidence interval {CI}, 0.90-0.97] and 0.86 [95{\%} CI, 0.80-0.93], respectively). NIS (score >=2) was independently related to poor nutrition-related clinical outcome (odds ratio [OR], 3.03; 95{\%} CI, 1.47-6.20) and mortality (OR, 1.11; 95{\%} CI, 1.03-1.20) adjusted for age, dialysis vintage, serum albumin level, and comorbidities. CONCLUSIONS: NIS score is a promising nutritional screening tool for the identification of patients receiving hemodialysis who are at risk of malnutrition and poor clinical outcome. Further research is required to investigate the reliability and utility of this tool in a larger population group.",
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Role of nutrition impact symptoms in predicting nutritional status and clinical outcome in hemodialysis patients : A potential screening tool. / Campbell, Katrina L; Bauer, Judith D; Ikehiro, Aya; Johnson, David W.

In: Journal of Renal Nutrition, Vol. 23, No. 4, 01.07.2013, p. 302-307.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Role of nutrition impact symptoms in predicting nutritional status and clinical outcome in hemodialysis patients

T2 - A potential screening tool

AU - Campbell, Katrina L

AU - Bauer, Judith D

AU - Ikehiro, Aya

AU - Johnson, David W.

PY - 2013/7/1

Y1 - 2013/7/1

N2 - OBJECTIVE: This study aims to establish the utility of the Nutrition Impact Symptoms (NIS), a part of the Patient-Generated Subjective Global Assessment (PG-SGA) as a nutritional screening tool in patients receiving hemodialysis (HD). DESIGN: This was a prospective observational study. SETTING: The study took place in a single public tertiary in-center dialysis facility in Australia. SUBJECTS: Patients included 213 individuals receiving maintenance HD for at least 3 months who were older than 18 years of age (mean age, 58.9 ± 16.3 years; 55.4% [n = 118] male patients). MAIN OUTCOME MEASURE: Malnutrition, which was classified by the Subjective Global Assessment rating (SGA, B or C) and the nutrition-related clinical outcome (decline in weight [>5%], SGA, reduction in serum albumin [>5 g/L]), or 12-month mortality. RESULTS: Patients assessed as malnourished totaled 23.5% (n = 50). Total PG-SGA and NIS scores showed a comparable ability to predict malnutrition (area under the curve, 0.93 [95% confidence interval {CI}, 0.90-0.97] and 0.86 [95% CI, 0.80-0.93], respectively). NIS (score >=2) was independently related to poor nutrition-related clinical outcome (odds ratio [OR], 3.03; 95% CI, 1.47-6.20) and mortality (OR, 1.11; 95% CI, 1.03-1.20) adjusted for age, dialysis vintage, serum albumin level, and comorbidities. CONCLUSIONS: NIS score is a promising nutritional screening tool for the identification of patients receiving hemodialysis who are at risk of malnutrition and poor clinical outcome. Further research is required to investigate the reliability and utility of this tool in a larger population group.

AB - OBJECTIVE: This study aims to establish the utility of the Nutrition Impact Symptoms (NIS), a part of the Patient-Generated Subjective Global Assessment (PG-SGA) as a nutritional screening tool in patients receiving hemodialysis (HD). DESIGN: This was a prospective observational study. SETTING: The study took place in a single public tertiary in-center dialysis facility in Australia. SUBJECTS: Patients included 213 individuals receiving maintenance HD for at least 3 months who were older than 18 years of age (mean age, 58.9 ± 16.3 years; 55.4% [n = 118] male patients). MAIN OUTCOME MEASURE: Malnutrition, which was classified by the Subjective Global Assessment rating (SGA, B or C) and the nutrition-related clinical outcome (decline in weight [>5%], SGA, reduction in serum albumin [>5 g/L]), or 12-month mortality. RESULTS: Patients assessed as malnourished totaled 23.5% (n = 50). Total PG-SGA and NIS scores showed a comparable ability to predict malnutrition (area under the curve, 0.93 [95% confidence interval {CI}, 0.90-0.97] and 0.86 [95% CI, 0.80-0.93], respectively). NIS (score >=2) was independently related to poor nutrition-related clinical outcome (odds ratio [OR], 3.03; 95% CI, 1.47-6.20) and mortality (OR, 1.11; 95% CI, 1.03-1.20) adjusted for age, dialysis vintage, serum albumin level, and comorbidities. CONCLUSIONS: NIS score is a promising nutritional screening tool for the identification of patients receiving hemodialysis who are at risk of malnutrition and poor clinical outcome. Further research is required to investigate the reliability and utility of this tool in a larger population group.

U2 - 10.1053/j.jrn.2012.07.001

DO - 10.1053/j.jrn.2012.07.001

M3 - Article

VL - 23

SP - 302

EP - 307

JO - Journal of Renal Nutrition

JF - Journal of Renal Nutrition

SN - 1051-2276

IS - 4

ER -