Risk of tuberculosis during pregnancy in Mongolia, a high incidence setting with low HIV prevalence

N. L. Rendell*, N. Batjargal, N. Jadambaa, C. C. Dobler

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Abstract

OBJECTIVE : To investigate the epidemiology and the relative risk of tuberculosis (TB) in pregnant women in Mongolia, a high TB incidence setting with a low rate of human immunodeficiency virus co-infection, where active case finding for TB in pregnancy is implemented. DESIGN: We retrospectively collected data on pregnant women diagnosed with TB during 2013. Data were collected through doctors at central TB dispensaries who extracted the relevant information from patients' clinical records. RESULT S : The overall incidence of TB among pregnant women was 228 (95%CI 187-276) per 100 000 personyears, resulting in an incidence rate ratio of 1.31 (95%CI 1.08-1.59) in pregnant women compared to the general population. Twelve per cent of the pregnant women with TB chose to have an abortion. CONCLUS IONS : In this study, pregnant women had a 1.3-fold higher risk of developing TB than the general population. Based on a moderately increased risk of TB during pregnancy in our study and the potential for adverse health outcomes, TB screening among pregnant women can currently be justified, but the cost-effectiveness of this intervention remains unclear. Patients and doctors need to be educated about the safety of standard TB treatment in pregnancy to reduce the rate of abortions.

Original languageEnglish
Pages (from-to)1615-1620
Number of pages6
JournalInternational Journal of Tuberculosis and Lung Disease
Volume20
Issue number12
DOIs
Publication statusPublished - 1 Dec 2016
Externally publishedYes

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