Reforming disease definitions: A new primary care led, people-centred approach

Ray Moynihan, John Brodersen, Iona Heath, Minna Johannson, Thomas Kuehlein, Sergio Minué-Lorenzo, Halfdan Petursson, Miguel Pizzanelli, Susanne Reventlow, Johann Sigurdsson, Anna Stavdal, Julian Treadwell, Paul Glasziou

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)


Expanding disease definitions are causing more and more previously healthy people to be labelled as diseased, contributing to the problem of overdiagnosis and related overtreatment. Often the specialist guideline panels which expand definitions have close tis to industry and do not investigate the harms of defining more people as sick. Responding to growing calls to address these problems, an international group of leading researchers and clinicians is proposing a new way to set diagnostic thresholds and mark the boundaries of condition definitions, to try to tackle a key driver of overdiagnosis and overtreatment. The group proposes new evidence-informed principles, with new process and new people constituting new multi-disciplinary panels, free from financial conflicts of interest.
Original languageEnglish
Pages (from-to)170-173
Number of pages4
JournalBMJ Evidence-Based Medicine
Issue number5
Early online date8 Apr 2019
Publication statusPublished - 1 Oct 2019


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