Rapidly mutating Y-STRs multiplex genotyping panel to investigate UAE population

R. Alghafri, W. Goodwin, S. Hadi

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Development of a new multiplex comprising of 13 Rapidly Mutating Y STRs (RM Y-STR) is presented. The multiplex will aid investigating the human genetic structure of United Arab Emirates (UAE) populations and would also be used to investigate unresolved forensic cases in Dubai Forensic Laboratory. Thirteen markers have been included in the multiplex. A mini validation of the new multiplex has been carried out including specificity, sensitivity and mixture studies. These markers have been analysed in 600 male samples from UAE population. Allelic frequencies, haplotype diversity and discrimination capacity were determined for the 13 RM Y-STRs. Mutations pattern analysis of the RM Y-STR loci in a typical UAE family has also been carried out.

Original languageEnglish
JournalForensic Science International: Genetics Supplement Series
Volume4
Issue number1
DOIs
Publication statusPublished - 30 Oct 2013
Externally publishedYes

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United Arab Emirates
Population
Genetic Structures
Medical Genetics
Haplotypes
Sensitivity and Specificity
Mutation

Cite this

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Rapidly mutating Y-STRs multiplex genotyping panel to investigate UAE population. / Alghafri, R.; Goodwin, W.; Hadi, S.

In: Forensic Science International: Genetics Supplement Series, Vol. 4, No. 1, 30.10.2013.

Research output: Contribution to journalArticleResearchpeer-review

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