Prophylactic swallowing therapy for patients with head and neck cancer: A three-arm randomized parallel-group trial

Laurelie R. Wall*, Elizabeth C. Ward, Bena Cartmill, Anne J. Hill, Elizabeth Isenring, Joshua Byrnes, Sandro V. Porceddu

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Abstract

Background - Intensive prophylactic swallowing therapy can mitigate dysphagia in patients with oropharyngeal (OP) SCC, however, presents service challenges. This trial investigated the clinical efficacy of three service models delivering prophylactic swallowing therapy during (chemo)radiotherapy ([C]RT). 

Methods - Patients (n = 79) with OPSCC receiving (C)RT were were randomized to: (a) clinician-directed face-to-face therapy (n = 26); (b) telepractice therapy via "SwallowIT" (n = 26); or (c) patient self-directed therapy (n = 27). Swallowing, nutritional, and functional status were compared at baseline, 6-weeks, and 3-months post-(C)RT. Patients' perceptions/preferences for service-delivery were collated posttreatment. 

Results - Service-delivery mode did not affect clinical outcomes, with no significant (P > .05) between-group differences or group-by-time interactions observed for swallowing, nutrition, or functional measures. Therapy adherence declined during (C)RT in all groups. SwallowIT and clinician-directed models were preferred by significantly (P = .002) more patients than patient-directed. 

Conclusions - SwallowIT provided clinically equivalent outcomes to traditional service models. SwallowIT and clinician-directed therapy were preferred by patients, likely due to higher levels of therapy support.

Original languageEnglish
Pages (from-to)873-885
Number of pages13
JournalHead and Neck
Volume42
Issue number5
Early online date6 Jan 2020
DOIs
Publication statusPublished - May 2020

Fingerprint Dive into the research topics of 'Prophylactic swallowing therapy for patients with head and neck cancer: A three-arm randomized parallel-group trial'. Together they form a unique fingerprint.

Cite this