Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function: Effect on short-term outcomes

Hasanga Jayasekera, Ryan Harvey, Nigel Pinto, Julie Mundy, Annabel Wood, Elaine Beller, Paul Peters, Pallav Shah

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

BACKGROUND: This study evaluated the impact of decreasing renal function on short-term outcomes in patients undergoing primary coronary artery bypass grafting (CABG).

METHODS: The study period was from February 1999 to February 2009. Data on 4050 patients undergoing primary CABG were prospectively collected and analyzed retrospectively. The study population was divided into 3 groups: the CABG:N group, patients with preoperative serum creatinine levels <2 mg/dL (n = 3947); the CABG:RF group, patients with preoperative creatinine levels >2 mg/dL (n = 87); and the CABG:D group, patients on dialysis (n = 16).

RESULTS: The significant differences between the groups (CABG:D > CABG:RF > CABG:N) in short-term outcomes were with respect to blood product use (P < .001), postoperative acute myocardial infarction (P < .001), pulmonary complications (P .001), infection (P < .001), and death (P < .001). The risk of short-term death (30 days) in the CABG:D group (4/16, 25%) was 25 times greater than that in the CABG:N group (38/3947, 0.96%).

CONCLUSION: CABG in the presence of renal failure is associated with significant morbidity and mortality.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalHeart Surgery Forum
Volume15
Issue number2
DOIs
Publication statusPublished - Apr 2012
Externally publishedYes

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Coronary Artery Bypass
Kidney
Renal Insufficiency
Dialysis
Creatinine
Myocardial Infarction
Morbidity
Lung
Mortality
Infection
Serum

Cite this

Jayasekera, Hasanga ; Harvey, Ryan ; Pinto, Nigel ; Mundy, Julie ; Wood, Annabel ; Beller, Elaine ; Peters, Paul ; Shah, Pallav. / Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function : Effect on short-term outcomes. In: Heart Surgery Forum. 2012 ; Vol. 15, No. 2. pp. 69-72.
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title = "Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function: Effect on short-term outcomes",
abstract = "BACKGROUND: This study evaluated the impact of decreasing renal function on short-term outcomes in patients undergoing primary coronary artery bypass grafting (CABG).METHODS: The study period was from February 1999 to February 2009. Data on 4050 patients undergoing primary CABG were prospectively collected and analyzed retrospectively. The study population was divided into 3 groups: the CABG:N group, patients with preoperative serum creatinine levels <2 mg/dL (n = 3947); the CABG:RF group, patients with preoperative creatinine levels >2 mg/dL (n = 87); and the CABG:D group, patients on dialysis (n = 16).RESULTS: The significant differences between the groups (CABG:D > CABG:RF > CABG:N) in short-term outcomes were with respect to blood product use (P < .001), postoperative acute myocardial infarction (P < .001), pulmonary complications (P .001), infection (P < .001), and death (P < .001). The risk of short-term death (30 days) in the CABG:D group (4/16, 25{\%}) was 25 times greater than that in the CABG:N group (38/3947, 0.96{\%}).CONCLUSION: CABG in the presence of renal failure is associated with significant morbidity and mortality.",
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Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function : Effect on short-term outcomes. / Jayasekera, Hasanga; Harvey, Ryan; Pinto, Nigel; Mundy, Julie; Wood, Annabel; Beller, Elaine; Peters, Paul; Shah, Pallav.

In: Heart Surgery Forum, Vol. 15, No. 2, 04.2012, p. 69-72.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Primary coronary artery bypass surgery in the presence of decreasing preoperative renal function

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AU - Jayasekera, Hasanga

AU - Harvey, Ryan

AU - Pinto, Nigel

AU - Mundy, Julie

AU - Wood, Annabel

AU - Beller, Elaine

AU - Peters, Paul

AU - Shah, Pallav

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N2 - BACKGROUND: This study evaluated the impact of decreasing renal function on short-term outcomes in patients undergoing primary coronary artery bypass grafting (CABG).METHODS: The study period was from February 1999 to February 2009. Data on 4050 patients undergoing primary CABG were prospectively collected and analyzed retrospectively. The study population was divided into 3 groups: the CABG:N group, patients with preoperative serum creatinine levels <2 mg/dL (n = 3947); the CABG:RF group, patients with preoperative creatinine levels >2 mg/dL (n = 87); and the CABG:D group, patients on dialysis (n = 16).RESULTS: The significant differences between the groups (CABG:D > CABG:RF > CABG:N) in short-term outcomes were with respect to blood product use (P < .001), postoperative acute myocardial infarction (P < .001), pulmonary complications (P .001), infection (P < .001), and death (P < .001). The risk of short-term death (30 days) in the CABG:D group (4/16, 25%) was 25 times greater than that in the CABG:N group (38/3947, 0.96%).CONCLUSION: CABG in the presence of renal failure is associated with significant morbidity and mortality.

AB - BACKGROUND: This study evaluated the impact of decreasing renal function on short-term outcomes in patients undergoing primary coronary artery bypass grafting (CABG).METHODS: The study period was from February 1999 to February 2009. Data on 4050 patients undergoing primary CABG were prospectively collected and analyzed retrospectively. The study population was divided into 3 groups: the CABG:N group, patients with preoperative serum creatinine levels <2 mg/dL (n = 3947); the CABG:RF group, patients with preoperative creatinine levels >2 mg/dL (n = 87); and the CABG:D group, patients on dialysis (n = 16).RESULTS: The significant differences between the groups (CABG:D > CABG:RF > CABG:N) in short-term outcomes were with respect to blood product use (P < .001), postoperative acute myocardial infarction (P < .001), pulmonary complications (P .001), infection (P < .001), and death (P < .001). The risk of short-term death (30 days) in the CABG:D group (4/16, 25%) was 25 times greater than that in the CABG:N group (38/3947, 0.96%).CONCLUSION: CABG in the presence of renal failure is associated with significant morbidity and mortality.

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