Prevention of gestational diabetes: Feasibility issues for an exercise intervention in obese pregnant women

Leonie K. Callaway, Paul B. Colditz, Nuala M. Byrne, Barbara E. Lingwood, Ingrid J. Rowlands, Katie Foxcroft, H. David McIntyre

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Abstract

OBJECTIVE - To examine the feasibility of an individualized exercise program to prevent gestational diabetes mellitus (GDM) in obese pregnant women. RESEARCH DESIGN AND METHODS - The study was a pilot randomized controlled trial with obese pregnant women (intervention group, individualized exercise program [n = 25]; control group, usual care [n = 25]). Average weekly energy expenditure (MET hours per week and kilocalories per week) of exercise-specific activity was assessed during pregnancy using the Pregnancy Physical Activity Questionnaire. Fasting glucose and insulin and homeostasis model assessment of insulin resistance (HOMA-IR) were assessed at baseline and 20, 28, and 36 weeks' gestation. RESULTS - Of the women in the intervention group, 16 of 22 (73%) achieved more than 900 kcal/week of exercise-based activity at 28 weeks compared with 8 of 19 women in the control group (42%), P = 0.047. However, insulin resistance (HOMA-IR) did not differ between the groups. CONCLUSION - This intervention was feasible and prompted a modest increase in physical activity. However, we are not confident that this intervention would be sufficient to prevent GDM.

Original languageEnglish
Pages (from-to)1457-1459
Number of pages3
JournalDiabetes Care
Volume33
Issue number7
DOIs
Publication statusPublished - Jul 2010
Externally publishedYes

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    Callaway, L. K., Colditz, P. B., Byrne, N. M., Lingwood, B. E., Rowlands, I. J., Foxcroft, K., & McIntyre, H. D. (2010). Prevention of gestational diabetes: Feasibility issues for an exercise intervention in obese pregnant women. Diabetes Care, 33(7), 1457-1459. https://doi.org/10.2337/dc09-2336