Prevention of gestational diabetes: Feasibility issues for an exercise intervention in obese pregnant women

Leonie K. Callaway, Paul B. Colditz, Nuala M. Byrne, Barbara E. Lingwood, Ingrid J. Rowlands, Katie Foxcroft, H. David McIntyre

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Abstract

OBJECTIVE - To examine the feasibility of an individualized exercise program to prevent gestational diabetes mellitus (GDM) in obese pregnant women. RESEARCH DESIGN AND METHODS - The study was a pilot randomized controlled trial with obese pregnant women (intervention group, individualized exercise program [n = 25]; control group, usual care [n = 25]). Average weekly energy expenditure (MET hours per week and kilocalories per week) of exercise-specific activity was assessed during pregnancy using the Pregnancy Physical Activity Questionnaire. Fasting glucose and insulin and homeostasis model assessment of insulin resistance (HOMA-IR) were assessed at baseline and 20, 28, and 36 weeks' gestation. RESULTS - Of the women in the intervention group, 16 of 22 (73%) achieved more than 900 kcal/week of exercise-based activity at 28 weeks compared with 8 of 19 women in the control group (42%), P = 0.047. However, insulin resistance (HOMA-IR) did not differ between the groups. CONCLUSION - This intervention was feasible and prompted a modest increase in physical activity. However, we are not confident that this intervention would be sufficient to prevent GDM.

Original languageEnglish
Pages (from-to)1457-1459
Number of pages3
JournalDiabetes Care
Volume33
Issue number7
DOIs
Publication statusPublished - Jul 2010
Externally publishedYes

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Gestational Diabetes
Pregnant Women
Exercise
Insulin Resistance
Pregnancy
Homeostasis
Control Groups
Energy Metabolism
Fasting
Research Design
Randomized Controlled Trials
Insulin
Glucose

Cite this

Callaway, L. K., Colditz, P. B., Byrne, N. M., Lingwood, B. E., Rowlands, I. J., Foxcroft, K., & McIntyre, H. D. (2010). Prevention of gestational diabetes: Feasibility issues for an exercise intervention in obese pregnant women. Diabetes Care, 33(7), 1457-1459. https://doi.org/10.2337/dc09-2336
Callaway, Leonie K. ; Colditz, Paul B. ; Byrne, Nuala M. ; Lingwood, Barbara E. ; Rowlands, Ingrid J. ; Foxcroft, Katie ; McIntyre, H. David. / Prevention of gestational diabetes : Feasibility issues for an exercise intervention in obese pregnant women. In: Diabetes Care. 2010 ; Vol. 33, No. 7. pp. 1457-1459.
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Callaway, LK, Colditz, PB, Byrne, NM, Lingwood, BE, Rowlands, IJ, Foxcroft, K & McIntyre, HD 2010, 'Prevention of gestational diabetes: Feasibility issues for an exercise intervention in obese pregnant women' Diabetes Care, vol. 33, no. 7, pp. 1457-1459. https://doi.org/10.2337/dc09-2336

Prevention of gestational diabetes : Feasibility issues for an exercise intervention in obese pregnant women. / Callaway, Leonie K.; Colditz, Paul B.; Byrne, Nuala M.; Lingwood, Barbara E.; Rowlands, Ingrid J.; Foxcroft, Katie; McIntyre, H. David.

In: Diabetes Care, Vol. 33, No. 7, 07.2010, p. 1457-1459.

Research output: Contribution to journalArticleResearchpeer-review

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T2 - Feasibility issues for an exercise intervention in obese pregnant women

AU - Callaway, Leonie K.

AU - Colditz, Paul B.

AU - Byrne, Nuala M.

AU - Lingwood, Barbara E.

AU - Rowlands, Ingrid J.

AU - Foxcroft, Katie

AU - McIntyre, H. David

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Callaway LK, Colditz PB, Byrne NM, Lingwood BE, Rowlands IJ, Foxcroft K et al. Prevention of gestational diabetes: Feasibility issues for an exercise intervention in obese pregnant women. Diabetes Care. 2010 Jul;33(7):1457-1459. https://doi.org/10.2337/dc09-2336