Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair

Matthew John Burstow, Rossita Mohamad Yunus, Shahjahan Khan, Breda Memon, Muhammed Memon

Research output: Contribution to conferencePaperResearchpeer-review

Abstract

Purpose: The aim was to conduct a meta-analysis of the randomized evidence to determine the relative merits of laparoscopic inguinal herniorrhaphy (LIHR) and open inguinal herniorrhaphy (OIHR).
Data Sources and Review Methods: A search of the Medline, Embase, Science Citation Index, Current Contents and PubMed databases identified all randomized clinical trials (RCTs) that compared LIHR and OIHR published in the English literature between January 1990 and January 2007. The six outcome variables analysed ere operating time, hospital stay, return to normal activity, return to work, total complications and recurrence rate. Random effects meta-analyses were performed using odds ratios and weighted mean differences.
Results: Fifty-nine trials were considered suitable for the meta-analysis. A total of 8092 patients underwent LIHR and 8580 had OIHR. For three of the six outcomes the summary point estimates favoured LIHR over OIHR; there was a significant reduction of 34% in the relative odds of postoperative complications, 4.99 days in time to return to normal activity and 6.39 days 107 in time to return to work. However, there was a significant increase of 14.08 min in the mean operating time for LIHR. The relative odds of short term recurrence increased by 20 percent for LIHR compared with OIHR. There was a small trend towards decreased duration of hospital stay for LIHR compared with OIHR, although these results were not statistically significant.
Conclusions: Based on this meta-analysis, LIHR offers patients a number of benefits over OIHR at the expense of longer operating time but comparable recurrence rate and hospital stay.
Original languageEnglish
Pages106-118
Number of pages13
Publication statusPublished - 2010
EventTenth Islamic Countries Conference on Statistical Science: Statistics for development and good governance - Cairo, Egypt
Duration: 20 Dec 200923 Dec 2009
Conference number: 10
https://www.iccs-x.org.eg

Conference

ConferenceTenth Islamic Countries Conference on Statistical Science
CountryEgypt
CityCairo
Period20/12/0923/12/09
Internet address

Fingerprint

Groin
Inguinal Hernia
Herniorrhaphy
Meta-Analysis
Length of Stay
Return to Work
Odds Ratio
Recurrence
Literature
Information Storage and Retrieval
PubMed

Cite this

Burstow, M. J., Mohamad Yunus, R., Khan, S., Memon, B., & Memon, M. (2010). Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair. 106-118. Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.
Burstow, Matthew John ; Mohamad Yunus, Rossita ; Khan, Shahjahan ; Memon, Breda ; Memon, Muhammed. / Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair. Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.13 p.
@conference{ae28e661fa3846e0b8e35d2bfa7ee78f,
title = "Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair",
abstract = "Purpose: The aim was to conduct a meta-analysis of the randomized evidence to determine the relative merits of laparoscopic inguinal herniorrhaphy (LIHR) and open inguinal herniorrhaphy (OIHR).Data Sources and Review Methods: A search of the Medline, Embase, Science Citation Index, Current Contents and PubMed databases identified all randomized clinical trials (RCTs) that compared LIHR and OIHR published in the English literature between January 1990 and January 2007. The six outcome variables analysed ere operating time, hospital stay, return to normal activity, return to work, total complications and recurrence rate. Random effects meta-analyses were performed using odds ratios and weighted mean differences.Results: Fifty-nine trials were considered suitable for the meta-analysis. A total of 8092 patients underwent LIHR and 8580 had OIHR. For three of the six outcomes the summary point estimates favoured LIHR over OIHR; there was a significant reduction of 34{\%} in the relative odds of postoperative complications, 4.99 days in time to return to normal activity and 6.39 days 107 in time to return to work. However, there was a significant increase of 14.08 min in the mean operating time for LIHR. The relative odds of short term recurrence increased by 20 percent for LIHR compared with OIHR. There was a small trend towards decreased duration of hospital stay for LIHR compared with OIHR, although these results were not statistically significant. Conclusions: Based on this meta-analysis, LIHR offers patients a number of benefits over OIHR at the expense of longer operating time but comparable recurrence rate and hospital stay.",
author = "Burstow, {Matthew John} and {Mohamad Yunus}, Rossita and Shahjahan Khan and Breda Memon and Muhammed Memon",
year = "2010",
language = "English",
pages = "106--118",
note = "Tenth Islamic Countries Conference on Statistical Science : Statistics for development and good governance ; Conference date: 20-12-2009 Through 23-12-2009",
url = "https://www.iccs-x.org.eg",

}

Burstow, MJ, Mohamad Yunus, R, Khan, S, Memon, B & Memon, M 2010, 'Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair' Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt, 20/12/09 - 23/12/09, pp. 106-118.

Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair. / Burstow, Matthew John; Mohamad Yunus, Rossita; Khan, Shahjahan; Memon, Breda; Memon, Muhammed.

2010. 106-118 Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.

Research output: Contribution to conferencePaperResearchpeer-review

TY - CONF

T1 - Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair

AU - Burstow, Matthew John

AU - Mohamad Yunus, Rossita

AU - Khan, Shahjahan

AU - Memon, Breda

AU - Memon, Muhammed

PY - 2010

Y1 - 2010

N2 - Purpose: The aim was to conduct a meta-analysis of the randomized evidence to determine the relative merits of laparoscopic inguinal herniorrhaphy (LIHR) and open inguinal herniorrhaphy (OIHR).Data Sources and Review Methods: A search of the Medline, Embase, Science Citation Index, Current Contents and PubMed databases identified all randomized clinical trials (RCTs) that compared LIHR and OIHR published in the English literature between January 1990 and January 2007. The six outcome variables analysed ere operating time, hospital stay, return to normal activity, return to work, total complications and recurrence rate. Random effects meta-analyses were performed using odds ratios and weighted mean differences.Results: Fifty-nine trials were considered suitable for the meta-analysis. A total of 8092 patients underwent LIHR and 8580 had OIHR. For three of the six outcomes the summary point estimates favoured LIHR over OIHR; there was a significant reduction of 34% in the relative odds of postoperative complications, 4.99 days in time to return to normal activity and 6.39 days 107 in time to return to work. However, there was a significant increase of 14.08 min in the mean operating time for LIHR. The relative odds of short term recurrence increased by 20 percent for LIHR compared with OIHR. There was a small trend towards decreased duration of hospital stay for LIHR compared with OIHR, although these results were not statistically significant. Conclusions: Based on this meta-analysis, LIHR offers patients a number of benefits over OIHR at the expense of longer operating time but comparable recurrence rate and hospital stay.

AB - Purpose: The aim was to conduct a meta-analysis of the randomized evidence to determine the relative merits of laparoscopic inguinal herniorrhaphy (LIHR) and open inguinal herniorrhaphy (OIHR).Data Sources and Review Methods: A search of the Medline, Embase, Science Citation Index, Current Contents and PubMed databases identified all randomized clinical trials (RCTs) that compared LIHR and OIHR published in the English literature between January 1990 and January 2007. The six outcome variables analysed ere operating time, hospital stay, return to normal activity, return to work, total complications and recurrence rate. Random effects meta-analyses were performed using odds ratios and weighted mean differences.Results: Fifty-nine trials were considered suitable for the meta-analysis. A total of 8092 patients underwent LIHR and 8580 had OIHR. For three of the six outcomes the summary point estimates favoured LIHR over OIHR; there was a significant reduction of 34% in the relative odds of postoperative complications, 4.99 days in time to return to normal activity and 6.39 days 107 in time to return to work. However, there was a significant increase of 14.08 min in the mean operating time for LIHR. The relative odds of short term recurrence increased by 20 percent for LIHR compared with OIHR. There was a small trend towards decreased duration of hospital stay for LIHR compared with OIHR, although these results were not statistically significant. Conclusions: Based on this meta-analysis, LIHR offers patients a number of benefits over OIHR at the expense of longer operating time but comparable recurrence rate and hospital stay.

M3 - Paper

SP - 106

EP - 118

ER -

Burstow MJ, Mohamad Yunus R, Khan S, Memon B, Memon M. Preliminary results of meta-analysis of laparoscopic and open inguinal hernia repair. 2010. Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.