TY - JOUR
T1 - Pre-exercise carbohydrate status influences carbohydrate-mediated attenuation of post-exercise cytokine responses
AU - Cox, Amanda
AU - Pyne, D. B.
AU - Cox, G. R.
AU - Callister, R.
AU - Gleeson, M.
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Most studies investigating the effects of acute carbohydrate (CHO) ingestion on post-exercise cytokine responses have involved fasted athletes. This study characterised the effects of acute CHO beverage ingestion preceded by consumption of a CHO-containing pre-exercise meal. Sixteen highly-trained male cyclists/triathletes (age: 30.6±5.6y; V̇O2max: 64.8±4.7 ml·kg·min-1 [mean ± SD]) undertook two cycle ergometry trials involving randomised consumption of a 10% CHO beverage (15 mL·kg-1·hr-1) or water (H2O). Trials were undertaken 2 h after a breakfast providing 2.1 g CHO·kg-1 body mass (BM) (48 kJ·kg-1 BM) and consisted of 100 min steady state cycle ergometry at 70% V̇O2max followed by a time trial of ∼30 min duration. Blood samples were collected pre-, post- and 1 h post-exercise for measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance was not substantially different between CHO and H2O trials (4.5%, p = 0.42). Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to the H2O trial. There was a substantial reduction in IL-10 (32%, p = 0.05) and IL-1ra (43%, p = 0.02) responses at 1 h post-exercise with CHO compared to H2O ingestion. In conclusion, the previously shown attenuating effects of CHO ingestion during exercise on cytokine responses appear reduced when athletes consume a CHO-containing pre-exercise meal.
AB - Most studies investigating the effects of acute carbohydrate (CHO) ingestion on post-exercise cytokine responses have involved fasted athletes. This study characterised the effects of acute CHO beverage ingestion preceded by consumption of a CHO-containing pre-exercise meal. Sixteen highly-trained male cyclists/triathletes (age: 30.6±5.6y; V̇O2max: 64.8±4.7 ml·kg·min-1 [mean ± SD]) undertook two cycle ergometry trials involving randomised consumption of a 10% CHO beverage (15 mL·kg-1·hr-1) or water (H2O). Trials were undertaken 2 h after a breakfast providing 2.1 g CHO·kg-1 body mass (BM) (48 kJ·kg-1 BM) and consisted of 100 min steady state cycle ergometry at 70% V̇O2max followed by a time trial of ∼30 min duration. Blood samples were collected pre-, post- and 1 h post-exercise for measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance was not substantially different between CHO and H2O trials (4.5%, p = 0.42). Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to the H2O trial. There was a substantial reduction in IL-10 (32%, p = 0.05) and IL-1ra (43%, p = 0.02) responses at 1 h post-exercise with CHO compared to H2O ingestion. In conclusion, the previously shown attenuating effects of CHO ingestion during exercise on cytokine responses appear reduced when athletes consume a CHO-containing pre-exercise meal.
UR - http://www.scopus.com/inward/record.url?scp=57749169109&partnerID=8YFLogxK
U2 - 10.1055/s-2008-1038753
DO - 10.1055/s-2008-1038753
M3 - Article
C2 - 18615388
AN - SCOPUS:57749169109
SN - 0172-4622
VL - 29
SP - 1003
EP - 1009
JO - International Journal of Sports Medicine
JF - International Journal of Sports Medicine
IS - 12
ER -