Pre-exercise carbohydrate status influences carbohydrate-mediated attenuation of post-exercise cytokine responses

Amanda Cox, D. B. Pyne, G. R. Cox, R. Callister, M. Gleeson

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Abstract

Most studies investigating the effects of acute carbohydrate (CHO) ingestion on post-exercise cytokine responses have involved fasted athletes. This study characterised the effects of acute CHO beverage ingestion preceded by consumption of a CHO-containing pre-exercise meal. Sixteen highly-trained male cyclists/triathletes (age: 30.6±5.6y; V̇O2max: 64.8±4.7 ml·kg·min-1 [mean ± SD]) undertook two cycle ergometry trials involving randomised consumption of a 10% CHO beverage (15 mL·kg-1·hr-1) or water (H2O). Trials were undertaken 2 h after a breakfast providing 2.1 g CHO·kg-1 body mass (BM) (48 kJ·kg-1 BM) and consisted of 100 min steady state cycle ergometry at 70% V̇O2max followed by a time trial of ∼30 min duration. Blood samples were collected pre-, post- and 1 h post-exercise for measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance was not substantially different between CHO and H2O trials (4.5%, p = 0.42). Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to the H2O trial. There was a substantial reduction in IL-10 (32%, p = 0.05) and IL-1ra (43%, p = 0.02) responses at 1 h post-exercise with CHO compared to H2O ingestion. In conclusion, the previously shown attenuating effects of CHO ingestion during exercise on cytokine responses appear reduced when athletes consume a CHO-containing pre-exercise meal.

Original languageEnglish
Pages (from-to)1003-1009
Number of pages7
JournalInternational Journal of Sports Medicine
Volume29
Issue number12
DOIs
Publication statusPublished - 1 Dec 2008
Externally publishedYes

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Carbohydrates
Exercise
Cytokines
Eating
Ergometry
Interleukins
Beverages
Interleukin-8
Athletes
Interleukin-10
Meals
Interleukin-6
Breakfast
Water

Cite this

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title = "Pre-exercise carbohydrate status influences carbohydrate-mediated attenuation of post-exercise cytokine responses",
abstract = "Most studies investigating the effects of acute carbohydrate (CHO) ingestion on post-exercise cytokine responses have involved fasted athletes. This study characterised the effects of acute CHO beverage ingestion preceded by consumption of a CHO-containing pre-exercise meal. Sixteen highly-trained male cyclists/triathletes (age: 30.6±5.6y; V̇O2max: 64.8±4.7 ml·kg·min-1 [mean ± SD]) undertook two cycle ergometry trials involving randomised consumption of a 10{\%} CHO beverage (15 mL·kg-1·hr-1) or water (H2O). Trials were undertaken 2 h after a breakfast providing 2.1 g CHO·kg-1 body mass (BM) (48 kJ·kg-1 BM) and consisted of 100 min steady state cycle ergometry at 70{\%} V̇O2max followed by a time trial of ∼30 min duration. Blood samples were collected pre-, post- and 1 h post-exercise for measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance was not substantially different between CHO and H2O trials (4.5{\%}, p = 0.42). Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to the H2O trial. There was a substantial reduction in IL-10 (32{\%}, p = 0.05) and IL-1ra (43{\%}, p = 0.02) responses at 1 h post-exercise with CHO compared to H2O ingestion. In conclusion, the previously shown attenuating effects of CHO ingestion during exercise on cytokine responses appear reduced when athletes consume a CHO-containing pre-exercise meal.",
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Pre-exercise carbohydrate status influences carbohydrate-mediated attenuation of post-exercise cytokine responses. / Cox, Amanda; Pyne, D. B.; Cox, G. R.; Callister, R.; Gleeson, M.

In: International Journal of Sports Medicine, Vol. 29, No. 12, 01.12.2008, p. 1003-1009.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

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AU - Cox, Amanda

AU - Pyne, D. B.

AU - Cox, G. R.

AU - Callister, R.

AU - Gleeson, M.

PY - 2008/12/1

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N2 - Most studies investigating the effects of acute carbohydrate (CHO) ingestion on post-exercise cytokine responses have involved fasted athletes. This study characterised the effects of acute CHO beverage ingestion preceded by consumption of a CHO-containing pre-exercise meal. Sixteen highly-trained male cyclists/triathletes (age: 30.6±5.6y; V̇O2max: 64.8±4.7 ml·kg·min-1 [mean ± SD]) undertook two cycle ergometry trials involving randomised consumption of a 10% CHO beverage (15 mL·kg-1·hr-1) or water (H2O). Trials were undertaken 2 h after a breakfast providing 2.1 g CHO·kg-1 body mass (BM) (48 kJ·kg-1 BM) and consisted of 100 min steady state cycle ergometry at 70% V̇O2max followed by a time trial of ∼30 min duration. Blood samples were collected pre-, post- and 1 h post-exercise for measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance was not substantially different between CHO and H2O trials (4.5%, p = 0.42). Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to the H2O trial. There was a substantial reduction in IL-10 (32%, p = 0.05) and IL-1ra (43%, p = 0.02) responses at 1 h post-exercise with CHO compared to H2O ingestion. In conclusion, the previously shown attenuating effects of CHO ingestion during exercise on cytokine responses appear reduced when athletes consume a CHO-containing pre-exercise meal.

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M3 - Article

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JO - International Journal of Sports Medicine

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SN - 0172-4622

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