Physical inactivity, appetite regulation and obesity

Extract:
The sedentary lifestyle is associated with chronic disease and ill health. The asymmetrical pressures imposed by the environment which facilitate inactivity whilst simultaneously providing an increased opportunity to over-consume food promote a susceptibility to gain weight. the inability of the appetite system to down regulate food intake in response to inactivity compounds the problem. Exercise and dietary interventions could help by promoting a negative energy balance. However, individual variability and compensatory responses to energy balance perturbations need to be understood so that weight management can be tailored to suit individuals.