Phasic contractions of the pig bladder: Functional heterogeneity between bladder regions and the role of the mucosa

Helen Nyamwaro, Neil G. McKay, Kim Lawson, Christopher R. Chapple, Donna J Sellers

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Abstract

OAB, a LUT disorder defined by the ICS as urinary urgency with or without incontinence, is characterised by increased spontaneous or phasic bladder contractions (PCs) which are thought to originate from the mucosa, although the exact mechanism involved is still unclear. Immunohistological studies by Gillespie et al (2004a,b;2005) have shown possible heterogeneity of the urotheliumand suburothelial myofibroblasts between the trigone,lateral wall and dome of the bladder. The aim of the present study was to determine any functional heterogeneity in PCsin these bladder regions and the role of the mucosa.
Original languageEnglish
Article number123
Pages (from-to)71-71
Number of pages1
JournalEuropean Urology, Supplements
Volume9
Issue number2
DOIs
Publication statusPublished - 2010
Externally publishedYes

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Mucous Membrane
Urinary Bladder
Swine
Myofibroblasts

Cite this

Nyamwaro, Helen ; McKay, Neil G. ; Lawson, Kim ; Chapple, Christopher R. ; Sellers, Donna J. / Phasic contractions of the pig bladder: Functional heterogeneity between bladder regions and the role of the mucosa. In: European Urology, Supplements. 2010 ; Vol. 9, No. 2. pp. 71-71.
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abstract = "OAB, a LUT disorder defined by the ICS as urinary urgency with or without incontinence, is characterised by increased spontaneous or phasic bladder contractions (PCs) which are thought to originate from the mucosa, although the exact mechanism involved is still unclear. Immunohistological studies by Gillespie et al (2004a,b;2005) have shown possible heterogeneity of the urotheliumand suburothelial myofibroblasts between the trigone,lateral wall and dome of the bladder. The aim of the present study was to determine any functional heterogeneity in PCsin these bladder regions and the role of the mucosa.",
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Phasic contractions of the pig bladder: Functional heterogeneity between bladder regions and the role of the mucosa. / Nyamwaro, Helen; McKay, Neil G.; Lawson, Kim; Chapple, Christopher R.; Sellers, Donna J.

In: European Urology, Supplements, Vol. 9, No. 2, 123, 2010, p. 71-71.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

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T1 - Phasic contractions of the pig bladder: Functional heterogeneity between bladder regions and the role of the mucosa

AU - Nyamwaro, Helen

AU - McKay, Neil G.

AU - Lawson, Kim

AU - Chapple, Christopher R.

AU - Sellers, Donna J

PY - 2010

Y1 - 2010

N2 - OAB, a LUT disorder defined by the ICS as urinary urgency with or without incontinence, is characterised by increased spontaneous or phasic bladder contractions (PCs) which are thought to originate from the mucosa, although the exact mechanism involved is still unclear. Immunohistological studies by Gillespie et al (2004a,b;2005) have shown possible heterogeneity of the urotheliumand suburothelial myofibroblasts between the trigone,lateral wall and dome of the bladder. The aim of the present study was to determine any functional heterogeneity in PCsin these bladder regions and the role of the mucosa.

AB - OAB, a LUT disorder defined by the ICS as urinary urgency with or without incontinence, is characterised by increased spontaneous or phasic bladder contractions (PCs) which are thought to originate from the mucosa, although the exact mechanism involved is still unclear. Immunohistological studies by Gillespie et al (2004a,b;2005) have shown possible heterogeneity of the urotheliumand suburothelial myofibroblasts between the trigone,lateral wall and dome of the bladder. The aim of the present study was to determine any functional heterogeneity in PCsin these bladder regions and the role of the mucosa.

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DO - 10.1016/S1569-9056(10)60128-5

M3 - Meeting Abstract

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JO - European Urology, Supplements

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