TY - JOUR
T1 - Phasic contractions of the pig bladder: Functional heterogeneity between bladder regions and the role of the mucosa
AU - Nyamwaro, Helen
AU - McKay, Neil G.
AU - Lawson, Kim
AU - Chapple, Christopher R.
AU - Sellers, Donna J
PY - 2010
Y1 - 2010
N2 - OAB, a LUT disorder defined by the ICS as urinary urgency with or without incontinence, is characterised by increased spontaneous or phasic bladder contractions (PCs) which are thought to originate from the mucosa, although the exact mechanism involved is still unclear. Immunohistological studies by Gillespie et al (2004a,b;2005) have shown possible heterogeneity of the urotheliumand suburothelial myofibroblasts between the trigone,lateral wall and dome of the bladder. The aim of the present study was to determine any functional heterogeneity in PCsin these bladder regions and the role of the mucosa.
AB - OAB, a LUT disorder defined by the ICS as urinary urgency with or without incontinence, is characterised by increased spontaneous or phasic bladder contractions (PCs) which are thought to originate from the mucosa, although the exact mechanism involved is still unclear. Immunohistological studies by Gillespie et al (2004a,b;2005) have shown possible heterogeneity of the urotheliumand suburothelial myofibroblasts between the trigone,lateral wall and dome of the bladder. The aim of the present study was to determine any functional heterogeneity in PCsin these bladder regions and the role of the mucosa.
U2 - 10.1016/S1569-9056(10)60128-5
DO - 10.1016/S1569-9056(10)60128-5
M3 - Meeting Abstract
SN - 1569-9056
VL - 9
SP - 71
EP - 71
JO - European Urology, Supplements
JF - European Urology, Supplements
IS - 2
M1 - 123
ER -