TY - JOUR
T1 - Pharmacoepidemiology as a focus for clinical epidemiology in developing countries
AU - Guess, Harry A.
AU - Goldsmith, Charles H.
AU - Henry, David
AU - Strom, Brian L.
N1 - Funding Information:
Clinical epidemiology began at the University of Pennsylvania in 1978 with a grant from the Charles A. Dana Foundation. This provided the opportunity to establish a Clinical Epidemiology Unit based in the Section of General Internal Medicine. Currently the Clinical Epidemiology Unit includes 8 full-time faculty members, 20 affiliate faculty and 50 research and support staff. The research program in pharmacoepidemiology has five major thrusts. The first is the development of non-experimental methods to study beneficial drug effects. The second is the development of a large computerized database of Medicaid data as a research tool. The third has been collaborative research with the Slone Epidemiology Unit of Boston University in performing case-control studies of adverse drug effects. The fourth has been the performance of a series of ad hoc studies of adverse drug effects. The fifth and most recent initiative has been in the area of hospital-based pharmacoepidemiology in response to a requirement by the Joint Commission on the Accreditation of Health Care Organizations. It is now a condition of accreditation that U.S. hospitals develop programs to monitor adverse drug reactions and conduct drug utilization review. A compilation of curricular material for teaching in pharmacoepidemiology has been developed and an indexed database of references in pharmacoepidemiology has been compiled. Both of these have been made available to the other CERTCs. Finally, the INCLEN Director, Dr Brian Strom, has recently published a textbook of pharmacoepidemiology [6]. As to pharmacoepidemiology training, this program for health professionals is modeled after a biomedical fellowship program rather than a School of Public health degree. Essentially, this means less formal course work and more individually guided research. Trainees in pharmacoepidemiology take the usual clinical epidemiology courses, supplemented by additional pharmacoepidemiology tutorials and experience, depending on their interests and needs. Included would be courses in pharmacokinetics, work with the hospital-based phar-macoepidemiology program, and work with industry and/or the U.S. Food and Drug Administration (FDA). A pharmacoepidemiology research project is conceptualized, designed, and must be completed prior to receiving a degree. The M.S. degree in Clinical Epidemiology is awarded upon successful completion of the training program.
PY - 1991
Y1 - 1991
N2 - We present a concept of pharmacoepidemiology as a branch of clinical epidemiology having particular relevance to public health in developing countries. Planning to incorporate pharmacoepidemiology into the clinical epidemiology curriculum of the International Clinical Epidemiology Network (INCLEN) is discussed and an outline of training programs in pharmacoepidemiology at INCLEN universities is given.
AB - We present a concept of pharmacoepidemiology as a branch of clinical epidemiology having particular relevance to public health in developing countries. Planning to incorporate pharmacoepidemiology into the clinical epidemiology curriculum of the International Clinical Epidemiology Network (INCLEN) is discussed and an outline of training programs in pharmacoepidemiology at INCLEN universities is given.
UR - http://www.scopus.com/inward/record.url?scp=0025907745&partnerID=8YFLogxK
U2 - 10.1016/0895-4356(91)90120-X
DO - 10.1016/0895-4356(91)90120-X
M3 - Article
C2 - 2045835
AN - SCOPUS:0025907745
SN - 0895-4356
VL - 45
SP - 101
EP - 105
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
IS - Suppl. 2
ER -
