TY - JOUR
T1 - Neuraminidase inhibitors for influenza complications
AU - Del Mar, Chris
AU - Doshi, Peter
AU - Hama, Rokuro
AU - Jones, Mark
AU - Jefferson, Tom
AU - Heneghan, Carl
AU - Onakpoya, Igho
AU - Howick, Jeremy
PY - 2014/10/4
Y1 - 2014/10/4
N2 - In their Comment (Aug 2, p 386),1 Jonathan Nguyen-Van-Tam and colleagues suggest that findings from our Cochrane review2 and a study of observational data3 are consistent. In our review, which was based on full clinical study reports of all manufacturer-sponsored randomised trials, we did not find evidence that neuraminidase inhibitors improve important outcomes of influenza, whereas the Roche-funded individual analysis of a subset of retrospective case reports suggested that neuraminidase inhibitors do have some beneficial effect.
AB - In their Comment (Aug 2, p 386),1 Jonathan Nguyen-Van-Tam and colleagues suggest that findings from our Cochrane review2 and a study of observational data3 are consistent. In our review, which was based on full clinical study reports of all manufacturer-sponsored randomised trials, we did not find evidence that neuraminidase inhibitors improve important outcomes of influenza, whereas the Roche-funded individual analysis of a subset of retrospective case reports suggested that neuraminidase inhibitors do have some beneficial effect.
UR - http://www.scopus.com/inward/record.url?scp=84925286600&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(14)61761-X
DO - 10.1016/S0140-6736(14)61761-X
M3 - Letter
C2 - MEDLINE:25283565
AN - SCOPUS:84925286600
SN - 0140-6736
VL - 384
SP - 1260
EP - 1261
JO - The Lancet
JF - The Lancet
IS - 9950
ER -