Abstract
Aims: Mood and presumed sub-cortical and frontal lobe related traits were assessed in 100 in-patients undergoing treatment for substance use disorders and in a community control sample of 107 social drinkers.
Methods: Participants completed self-report measures of mood, alexithymia, dispositional mindfulness, frontal systems functioning, impulsivity, sensitivity to rewards and punishments, alcohol use, illicit drug use and demographic characteristics.
Results: Multivariate analysis of covariance (MANCOVA) controlling for age, education, previous serious head injury and gender revealed highly significant differences (p < .0001) between clinical and control groups on all dependent measures. The clinical group scored significantly higher on depression, anxiety, stress, alexithymia, frontal systems dysfunction, reward sensitivity, punishment sensitivity and impulsivity, and lower on dispositional mindfulness, than the control group. Time in treatment was significantly correlated only with levels of depression, anxiety and stress, supporting the relative stability of the trait measures.
Conclusions: Results are consistent with the notion that substance use disorders are linked to frontal lobe dysfunction and associated traits, although the current findings cannot determine whether such characteristics predated or post-dated disordered substance use.
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The abstract published in Vol 146 of 'Drug and Alcohol Dependence' was first submitted and presented at the annual meeting of the College on Problems of Drug Dependence (CPDD). The conference was held from June 14 to 19, 2014, in San Juan, Puerto Rico.
This abstract was published in the Conference Book of Abstracts on page 109 (link included).
Methods: Participants completed self-report measures of mood, alexithymia, dispositional mindfulness, frontal systems functioning, impulsivity, sensitivity to rewards and punishments, alcohol use, illicit drug use and demographic characteristics.
Results: Multivariate analysis of covariance (MANCOVA) controlling for age, education, previous serious head injury and gender revealed highly significant differences (p < .0001) between clinical and control groups on all dependent measures. The clinical group scored significantly higher on depression, anxiety, stress, alexithymia, frontal systems dysfunction, reward sensitivity, punishment sensitivity and impulsivity, and lower on dispositional mindfulness, than the control group. Time in treatment was significantly correlated only with levels of depression, anxiety and stress, supporting the relative stability of the trait measures.
Conclusions: Results are consistent with the notion that substance use disorders are linked to frontal lobe dysfunction and associated traits, although the current findings cannot determine whether such characteristics predated or post-dated disordered substance use.
********************
The abstract published in Vol 146 of 'Drug and Alcohol Dependence' was first submitted and presented at the annual meeting of the College on Problems of Drug Dependence (CPDD). The conference was held from June 14 to 19, 2014, in San Juan, Puerto Rico.
This abstract was published in the Conference Book of Abstracts on page 109 (link included).
| Original language | English |
|---|---|
| Pages (from-to) | e188-e189 |
| Number of pages | 1 |
| Journal | Drug and Alcohol Dependence |
| Volume | 146 |
| DOIs | |
| Publication status | Published - 2015 |
| Event | The College on Problems of Drug Dependence (CPDD) 76th Annual Meeting - San Juan, Puerto Rico Duration: 14 Jun 2014 → 19 Jun 2014 Conference number: 76th https://cpdd.org/meetings/annual-meeting-programs-abstracts/ |
