Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro

Sung Hyun Kang; Russ Chess-Williams; Catherine McDermott

Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro

Sung Hyun Kang, Russ Chess-Williams, Catherine McDermott

Research output: Contribution to conference › Abstract › Research › peer-review

Abstract

Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.

Original language	English
Pages	206-206
Number of pages	1
Publication status	Published - 2012
Event	Joint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia Duration: 2 Dec 2012 → 5 Dec 2012 http://www.ascept-apsa.com/

Conference

Conference	Joint ASCEPT- APSA 2012 Conference
Country/Territory	Australia
City	Sydney
Period	2/12/12 → 5/12/12
Internet address	http://www.ascept-apsa.com/

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http://www.ascept-apsa.com/wp-content/uploads/2012/07/ASCEPT-APSA-Poster-Abstracts-570-644.pdf

Cytotoxic Drugs and their Effects on Bladder Function
Author: Kang, S. H., 10 Oct 2015
Supervisor: McDermott, C. (Supervisor) & Chess-Williams, R. G. (Supervisor)
Student thesis: Doctoral Thesis

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@conference{988a9f08b5f94bd6a6358a564a4c895f,

title = "Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro",

abstract = "Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.",

author = "Kang, {Sung Hyun} and Russ Chess-Williams and Catherine McDermott",

year = "2012",

language = "English",

pages = "206--206",

note = "Joint ASCEPT- APSA 2012 Conference : Medication Safety ; Conference date: 02-12-2012 Through 05-12-2012",

url = "http://www.ascept-apsa.com/",

}

TY - CONF

T1 - Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro

AU - Kang, Sung Hyun

AU - Chess-Williams, Russ

AU - McDermott, Catherine

PY - 2012

Y1 - 2012

N2 - Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.

AB - Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.

M3 - Abstract

SP - 206

EP - 206

T2 - Joint ASCEPT- APSA 2012 Conference

Y2 - 2 December 2012 through 5 December 2012

ER -

Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro

Abstract

Conference

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Student theses

Cytotoxic Drugs and their Effects on Bladder Function

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