Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.
|Number of pages||1|
|Publication status||Published - 2012|
|Event||Joint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia|
Duration: 2 Dec 2012 → 5 Dec 2012
|Conference||Joint ASCEPT- APSA 2012 Conference|
|Period||2/12/12 → 5/12/12|
Kang, S. H., Chess-Williams, R., & McDermott, C. (2012). Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro. 206-206. Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia. http://www.ascept-apsa.com/wp-content/uploads/2012/07/ASCEPT-APSA-Poster-Abstracts-570-644.pdf