Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro

Research output: Contribution to conferenceAbstractResearchpeer-review


Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.
Original languageEnglish
Number of pages1
Publication statusPublished - 2012
EventJoint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia
Duration: 2 Dec 20125 Dec 2012


ConferenceJoint ASCEPT- APSA 2012 Conference
Internet address

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