Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro

Research output: Contribution to conferenceAbstractResearchpeer-review

Abstract

Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.
Original languageEnglish
Pages206-206
Number of pages1
Publication statusPublished - 2012
EventJoint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia
Duration: 2 Dec 20125 Dec 2012
http://www.ascept-apsa.com/

Conference

ConferenceJoint ASCEPT- APSA 2012 Conference
CountryAustralia
CitySydney
Period2/12/125/12/12
Internet address

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Contact Dermatitis
Mitomycin
Dinoprostone
Doxorubicin
Acetylcholine
Urinary Bladder
Adenosine Triphosphate
Drug Therapy
Therapeutics
In Vitro Techniques

Cite this

Kang, S. H., Chess-Williams, R., & McDermott, C. (2012). Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro. 206-206. Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia.
Kang, Sung Hyun ; Chess-Williams, Russ ; McDermott, Catherine. / Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro. Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia.1 p.
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abstract = "Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.",
author = "Kang, {Sung Hyun} and Russ Chess-Williams and Catherine McDermott",
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Kang, SH, Chess-Williams, R & McDermott, C 2012, 'Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro' Joint ASCEPT- APSA 2012 Conference , Sydney, Australia, 2/12/12 - 5/12/12, pp. 206-206.

Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro. / Kang, Sung Hyun; Chess-Williams, Russ; McDermott, Catherine.

2012. 206-206 Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia.

Research output: Contribution to conferenceAbstractResearchpeer-review

TY - CONF

T1 - Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro

AU - Kang, Sung Hyun

AU - Chess-Williams, Russ

AU - McDermott, Catherine

PY - 2012

Y1 - 2012

N2 - Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.

AB - Intravesical chemotherapy is commonly used for the treatment of cr. There is evidence of significant local adverse effects including contact dermatitis and symptoms of bladder overactivity. Doxorubicin has been shown to increase Ach and PGE2 release in human urothelial cells (Chess-Williams et al, 2012). Effects of mitomycin C (MMC) have not been investigated despite evidence of greater toxicity.

M3 - Abstract

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EP - 206

ER -

Kang SH, Chess-Williams R, McDermott C. Mitomycin C alters urothelial ATP, acetylcholine and PGE2 release in vitro. 2012. Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia.