Mechanisms determining innate resistance to ectromelia virus infection in C57BL mice

H C O'Neill, R V Blanden

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15 Citations (Scopus)

Abstract

The mechanism for innate resistance to ectromelia virus, which is controlled by a single gene in C57BL mice, was investigated. The cells or factors involved appear to be radioresistant and to impose an early barrier to viral penetration and spread via lymphatics or blood to the target organs, i.e., liver and spleen.

Original languageEnglish
Pages (from-to)1391-1394
Number of pages4
JournalInfection and Immunity
Volume41
Issue number3
Publication statusPublished - Sep 1983
Externally publishedYes

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Ectromelia virus
Virus Diseases
Inbred C57BL Mouse
Spleen
Liver
Genes

Cite this

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title = "Mechanisms determining innate resistance to ectromelia virus infection in C57BL mice",
abstract = "The mechanism for innate resistance to ectromelia virus, which is controlled by a single gene in C57BL mice, was investigated. The cells or factors involved appear to be radioresistant and to impose an early barrier to viral penetration and spread via lymphatics or blood to the target organs, i.e., liver and spleen.",
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Mechanisms determining innate resistance to ectromelia virus infection in C57BL mice. / O'Neill, H C; Blanden, R V.

In: Infection and Immunity, Vol. 41, No. 3, 09.1983, p. 1391-1394.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Blanden, R V

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AB - The mechanism for innate resistance to ectromelia virus, which is controlled by a single gene in C57BL mice, was investigated. The cells or factors involved appear to be radioresistant and to impose an early barrier to viral penetration and spread via lymphatics or blood to the target organs, i.e., liver and spleen.

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