Limitations in the inverse association between psychological resilience and depression in prostate cancer patients experiencing chronic physiological stress

Christopher F. Sharpley, David R H Christie, Vicki Bitsika, Linda L. Agnew, Nicholas M. Andronicos, Mary E McMillan, Timothy M Richards

    Research output: Contribution to journalArticleResearchpeer-review

    1 Citation (Scopus)

    Abstract

    Objective: To investigate the effect of chronic stress as measured in cortisol concentrations upon the association between psychological resilience (PR) and depression in prostate cancer (PCa) patients. 

    Methods: A total of 104 men with PCa completed inventories on PR, depression, and background factors, plus gave a sample of their saliva for cortisol assay. 

    Results: The inverse correlation between PR and depression was present only for PCa patients with low or moderate concentrations of salivary cortisol (when classified as more than 1.0 SD below the mean vs within 1.0 SD of the group mean) but not for those men whose cortisol was >1.0 SD from the group mean. Specific PR factors and behaviours that made the greatest contribution to depression were identified for the low and moderate cortisol groups. 

    Conclusions: These results suggest that there are particular aspects of PR that are most strongly related to depression, but that PR's inverse association with depression may be absent in participants with extreme chronic physiological stress.

    Original languageEnglish
    Pages (from-to)223-228
    Number of pages6
    JournalPsycho-Oncology
    Volume27
    Issue number1
    Early online date1 Aug 2017
    DOIs
    Publication statusPublished - 22 Jan 2018

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    Psychological Resilience
    Physiological Stress
    Prostatic Neoplasms
    Hydrocortisone
    Depression
    Saliva
    Psychology
    Equipment and Supplies

    Cite this

    Sharpley, C. F., Christie, D. R. H., Bitsika, V., Agnew, L. L., Andronicos, N. M., McMillan, M. E., & Richards, T. M. (2018). Limitations in the inverse association between psychological resilience and depression in prostate cancer patients experiencing chronic physiological stress. Psycho-Oncology, 27(1), 223-228. https://doi.org/10.1002/pon.4496
    Sharpley, Christopher F. ; Christie, David R H ; Bitsika, Vicki ; Agnew, Linda L. ; Andronicos, Nicholas M. ; McMillan, Mary E ; Richards, Timothy M. / Limitations in the inverse association between psychological resilience and depression in prostate cancer patients experiencing chronic physiological stress. In: Psycho-Oncology. 2018 ; Vol. 27, No. 1. pp. 223-228.
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    abstract = "Objective: To investigate the effect of chronic stress as measured in cortisol concentrations upon the association between psychological resilience (PR) and depression in prostate cancer (PCa) patients. Methods: A total of 104 men with PCa completed inventories on PR, depression, and background factors, plus gave a sample of their saliva for cortisol assay. Results: The inverse correlation between PR and depression was present only for PCa patients with low or moderate concentrations of salivary cortisol (when classified as more than 1.0 SD below the mean vs within 1.0 SD of the group mean) but not for those men whose cortisol was >1.0 SD from the group mean. Specific PR factors and behaviours that made the greatest contribution to depression were identified for the low and moderate cortisol groups. Conclusions: These results suggest that there are particular aspects of PR that are most strongly related to depression, but that PR's inverse association with depression may be absent in participants with extreme chronic physiological stress.",
    author = "Sharpley, {Christopher F.} and Christie, {David R H} and Vicki Bitsika and Agnew, {Linda L.} and Andronicos, {Nicholas M.} and McMillan, {Mary E} and Richards, {Timothy M}",
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    Sharpley, CF, Christie, DRH, Bitsika, V, Agnew, LL, Andronicos, NM, McMillan, ME & Richards, TM 2018, 'Limitations in the inverse association between psychological resilience and depression in prostate cancer patients experiencing chronic physiological stress' Psycho-Oncology, vol. 27, no. 1, pp. 223-228. https://doi.org/10.1002/pon.4496

    Limitations in the inverse association between psychological resilience and depression in prostate cancer patients experiencing chronic physiological stress. / Sharpley, Christopher F.; Christie, David R H; Bitsika, Vicki; Agnew, Linda L.; Andronicos, Nicholas M.; McMillan, Mary E; Richards, Timothy M.

    In: Psycho-Oncology, Vol. 27, No. 1, 22.01.2018, p. 223-228.

    Research output: Contribution to journalArticleResearchpeer-review

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    AU - Sharpley, Christopher F.

    AU - Christie, David R H

    AU - Bitsika, Vicki

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    AU - Andronicos, Nicholas M.

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    AU - Richards, Timothy M

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