TY - JOUR
T1 - Is afternoon cortisol more reliable than waking cortisol in association studies of children with an ASD?
AU - Sharpley, Christopher F.
AU - Bitsika, Vicki
AU - Andronicos, Nicholas M.
AU - Agnew, Linda L.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Salivary cortisol may be used as a biomarker of stress and anxiety in children with an Autism Spectrum Disorder (ASD) and is particularly valuable in studies of the association between stress-related cortisol concentrations and other factors such as comorbid disorders or aspects of the ASD phenotype. Although protocols for the collection of cortisol shortly after waking are often based on the assumption of the presence of a diurnal rhythm in cortisol, that rhythm may not be as reliable in children with an ASD as in non-ASD children. Alternatively, collecting cortisol during the afternoon may represent a more reliable procedure with less inter-participant variability.
AB - Salivary cortisol may be used as a biomarker of stress and anxiety in children with an Autism Spectrum Disorder (ASD) and is particularly valuable in studies of the association between stress-related cortisol concentrations and other factors such as comorbid disorders or aspects of the ASD phenotype. Although protocols for the collection of cortisol shortly after waking are often based on the assumption of the presence of a diurnal rhythm in cortisol, that rhythm may not be as reliable in children with an ASD as in non-ASD children. Alternatively, collecting cortisol during the afternoon may represent a more reliable procedure with less inter-participant variability.
UR - http://www.scopus.com/inward/record.url?scp=84951825243&partnerID=8YFLogxK
U2 - 10.1016/j.physbeh.2015.12.020
DO - 10.1016/j.physbeh.2015.12.020
M3 - Review article
AN - SCOPUS:84951825243
SN - 0031-9384
VL - 155
SP - 218
EP - 223
JO - Physiology and Behavior
JF - Physiology and Behavior
ER -