Introduction to systematic reviews and meta-analysis

Joanne E. McKenzie, Elaine M. Beller, Andrew B. Forbes

Research output: Contribution to journalReview articleResearchpeer-review

8 Citations (Scopus)

Abstract

Systematic reviews provide a method for collating and synthesizing research, and are used to inform healthcare decision making by clinicians, consumers and policy makers. A core component of many systematic reviews is a meta-analysis, which is a statistical synthesis of results across studies. In this review article, we introduce meta-analysis, focusing on the different meta-analysis models, their interpretation, how a model should be selected and discuss potential threats to the validity of meta-analyses. We illustrate the application of meta-analysis using data from a review examining the effects of early use of inhaled corticosteroids in the emergency department treatment of acute asthma.

Original languageEnglish
Pages (from-to)626-637
Number of pages12
JournalRespirology
Volume21
Issue number4
DOIs
Publication statusPublished - 1 May 2016

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Meta-Analysis
Emergency Treatment
Administrative Personnel
Hospital Emergency Service
Decision Making
Adrenal Cortex Hormones
Asthma
Delivery of Health Care
Research

Cite this

McKenzie, Joanne E. ; Beller, Elaine M. ; Forbes, Andrew B. / Introduction to systematic reviews and meta-analysis. In: Respirology. 2016 ; Vol. 21, No. 4. pp. 626-637.
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Introduction to systematic reviews and meta-analysis. / McKenzie, Joanne E.; Beller, Elaine M.; Forbes, Andrew B.

In: Respirology, Vol. 21, No. 4, 01.05.2016, p. 626-637.

Research output: Contribution to journalReview articleResearchpeer-review

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