Intracranial subdural empyema: A 10-year case series

Heath French, Nathan Schaefer, Gerben Keijzers, David Barison, Sarah Olson

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Abstract

Background: Intracranial subdural empyema (ISDE) is a pyogenic infection located in the space between the dura and arachnoid mater. Early diagnosis, prompt initiation of antimicrobial therapy, and surgical drainage are essential to reduce morbidity and mortality. This case series analyzes the presentation and management of ISDE in Queensland, Australia, over a 10-year period. Methods: Thirty-six patients with ISDE were treated at Gold Coast University Hospital, Princess Alexandra Hospital, Townsville Hospital, and Royal Brisbane Hospital. The patients' medical records were analyzed to ascertain patient demographics, etiology, presentation, and management. Results: A slight male preponderance occurred in the cohort of 36 patients with ISDE. The most common source of infection was a neurosurgical procedure, followed by sinusitis and otogenic sources. Headache, fever, and altered sensorium were the most common clinical triad of symptoms, present in 19 (53%) patients. Craniotomy was performed as the initial surgical procedure in 28 (88%) of the 32 patients who required surgery. Seizure prophylaxis was given to 25 (69%) patients, with 8 (32%) of those patients having seizures during their hospitalizations despite this therapy. Five (14%) patients required readmission and a second craniotomy because of failed resolution of the ISDE.

Original languageEnglish
Pages (from-to)188-194
Number of pages7
JournalOchsner Journal
Volume14
Issue number2
Publication statusPublished - 2014
Externally publishedYes

Fingerprint

Subdural Empyema
antineoplaston A10
Craniotomy
Seizures
Arachnoid
Neurosurgical Procedures
Patient Readmission
Dura Mater
Ghana
Queensland
Sinusitis
Infection
Medical Records
Headache
Early Diagnosis
Drainage
Hospitalization
Fever
Demography
Morbidity

Cite this

French, H., Schaefer, N., Keijzers, G., Barison, D., & Olson, S. (2014). Intracranial subdural empyema: A 10-year case series. Ochsner Journal, 14(2), 188-194.
French, Heath ; Schaefer, Nathan ; Keijzers, Gerben ; Barison, David ; Olson, Sarah. / Intracranial subdural empyema : A 10-year case series. In: Ochsner Journal. 2014 ; Vol. 14, No. 2. pp. 188-194.
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French, H, Schaefer, N, Keijzers, G, Barison, D & Olson, S 2014, 'Intracranial subdural empyema: A 10-year case series' Ochsner Journal, vol. 14, no. 2, pp. 188-194.

Intracranial subdural empyema : A 10-year case series. / French, Heath; Schaefer, Nathan; Keijzers, Gerben; Barison, David; Olson, Sarah.

In: Ochsner Journal, Vol. 14, No. 2, 2014, p. 188-194.

Research output: Contribution to journalArticleResearchpeer-review

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French H, Schaefer N, Keijzers G, Barison D, Olson S. Intracranial subdural empyema: A 10-year case series. Ochsner Journal. 2014;14(2):188-194.