Interventions for enhancing adherence to treatment in adults with bronchiectasis

Amanda McCullough, Elizabeth T. Thomas, Cristin Ryan, Judy M. Bradley, Brenda O'Neill, Stuart Elborn, Carmel Hughes

Research output: Contribution to journalArticleResearchpeer-review

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Abstract

Background

Bronchiectasis is characterised by a widening of the airways, leading to excess mucus production and recurrent infection. It is more prevalent in women and those in middle age. Many patients with bronchiectasis do not adhere to treatments (medications, exercise and airway clearance) prescribed for their condition. The best methods to change these adherence behaviours have not been identified.

Objectives

To assess the effects of interventions to enhance adherence to any aspect of treatment in adults with bronchiectasis in terms of adherence and health outcomes, such as pulmonary exacerbations, health-related quality of life and healthcare costs.

Search methods

We searched the Cochrane Airways Group Specialised Register (CAGR), which contains trial reports identified through systematic searches of CENTRAL, MEDLINE, EMBASE, CINAHL, AMED and PsycINFO, from inception to October 2015.

Selection criteria

We planned to include randomised controlled trials (RCTs) of adults with bronchiectasis that compared any intervention aimed at enhancing adherence versus no intervention, usual care or another adherence intervention. We excluded studies of those who had bronchiectasis due to cystic fibrosis.

Data collection and analysis

Two review authors (AMcC and ET) independently screened titles, abstracts and full-texts of identified studies.

Main results

Searches retrieved 36 studies reported in 37 articles; no eligible studies were identified.

Authors' conclusions

We did not identify any studies that assessed the effect of interventions to enhance adherence to treatment in bronchiectasis. Adequately powered, well-designed trials of adherence interventions for bronchiectasis are needed.

Original languageEnglish
Article numberCD011023
Number of pages17
JournalCochrane Database of Systematic Reviews
Volume2015
Issue number11
DOIs
Publication statusPublished - 18 Nov 2015

Cite this

McCullough, Amanda ; Thomas, Elizabeth T. ; Ryan, Cristin ; Bradley, Judy M. ; O'Neill, Brenda ; Elborn, Stuart ; Hughes, Carmel. / Interventions for enhancing adherence to treatment in adults with bronchiectasis. In: Cochrane Database of Systematic Reviews. 2015 ; Vol. 2015, No. 11.
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Interventions for enhancing adherence to treatment in adults with bronchiectasis. / McCullough, Amanda; Thomas, Elizabeth T.; Ryan, Cristin; Bradley, Judy M.; O'Neill, Brenda; Elborn, Stuart; Hughes, Carmel.

In: Cochrane Database of Systematic Reviews, Vol. 2015, No. 11, CD011023, 18.11.2015.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Interventions for enhancing adherence to treatment in adults with bronchiectasis

AU - McCullough, Amanda

AU - Thomas, Elizabeth T.

AU - Ryan, Cristin

AU - Bradley, Judy M.

AU - O'Neill, Brenda

AU - Elborn, Stuart

AU - Hughes, Carmel

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N2 - BackgroundBronchiectasis is characterised by a widening of the airways, leading to excess mucus production and recurrent infection. It is more prevalent in women and those in middle age. Many patients with bronchiectasis do not adhere to treatments (medications, exercise and airway clearance) prescribed for their condition. The best methods to change these adherence behaviours have not been identified.ObjectivesTo assess the effects of interventions to enhance adherence to any aspect of treatment in adults with bronchiectasis in terms of adherence and health outcomes, such as pulmonary exacerbations, health-related quality of life and healthcare costs.Search methodsWe searched the Cochrane Airways Group Specialised Register (CAGR), which contains trial reports identified through systematic searches of CENTRAL, MEDLINE, EMBASE, CINAHL, AMED and PsycINFO, from inception to October 2015.Selection criteriaWe planned to include randomised controlled trials (RCTs) of adults with bronchiectasis that compared any intervention aimed at enhancing adherence versus no intervention, usual care or another adherence intervention. We excluded studies of those who had bronchiectasis due to cystic fibrosis.Data collection and analysisTwo review authors (AMcC and ET) independently screened titles, abstracts and full-texts of identified studies.Main resultsSearches retrieved 36 studies reported in 37 articles; no eligible studies were identified.Authors' conclusionsWe did not identify any studies that assessed the effect of interventions to enhance adherence to treatment in bronchiectasis. Adequately powered, well-designed trials of adherence interventions for bronchiectasis are needed.

AB - BackgroundBronchiectasis is characterised by a widening of the airways, leading to excess mucus production and recurrent infection. It is more prevalent in women and those in middle age. Many patients with bronchiectasis do not adhere to treatments (medications, exercise and airway clearance) prescribed for their condition. The best methods to change these adherence behaviours have not been identified.ObjectivesTo assess the effects of interventions to enhance adherence to any aspect of treatment in adults with bronchiectasis in terms of adherence and health outcomes, such as pulmonary exacerbations, health-related quality of life and healthcare costs.Search methodsWe searched the Cochrane Airways Group Specialised Register (CAGR), which contains trial reports identified through systematic searches of CENTRAL, MEDLINE, EMBASE, CINAHL, AMED and PsycINFO, from inception to October 2015.Selection criteriaWe planned to include randomised controlled trials (RCTs) of adults with bronchiectasis that compared any intervention aimed at enhancing adherence versus no intervention, usual care or another adherence intervention. We excluded studies of those who had bronchiectasis due to cystic fibrosis.Data collection and analysisTwo review authors (AMcC and ET) independently screened titles, abstracts and full-texts of identified studies.Main resultsSearches retrieved 36 studies reported in 37 articles; no eligible studies were identified.Authors' conclusionsWe did not identify any studies that assessed the effect of interventions to enhance adherence to treatment in bronchiectasis. Adequately powered, well-designed trials of adherence interventions for bronchiectasis are needed.

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JO - Cochrane database of systematic reviews (Online)

JF - Cochrane database of systematic reviews (Online)

SN - 1469-493X

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M1 - CD011023

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