Interpreting diagnostic tests with continuous results and no gold standard: A common scenario explained using the tuberculin skin test

Claudia C. Dobler, M. Hassan Murad

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
1 Downloads (Pure)

Abstract

Practitioners of evidence-based medicine commonly encounter diagnostic tests with continuous results and no gold standard. In contrast, the traditional critical appraisal teachings assume a binary test (2×2 table) with a gold standard. In this guide, we use the example of the tuberculin skin test to illustrate a simple approach facilitated by using stratum-specific likelihood ratios and odds of developing future patient-important events. This approach can aid practitioners in the interpretation and application of diagnostic tests to patient care.

Original languageEnglish
Pages (from-to)199-201
Number of pages3
JournalBMJ Evidence-Based Medicine
Volume22
Issue number6
DOIs
Publication statusPublished - 1 Dec 2017
Externally publishedYes

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Tuberculin Test
Skin Tests
Routine Diagnostic Tests
Evidence-Based Medicine
Patient Care
Teaching
Odds Ratio

Cite this

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Interpreting diagnostic tests with continuous results and no gold standard : A common scenario explained using the tuberculin skin test. / Dobler, Claudia C.; Murad, M. Hassan.

In: BMJ Evidence-Based Medicine, Vol. 22, No. 6, 01.12.2017, p. 199-201.

Research output: Contribution to journalArticleResearchpeer-review

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