In patients with hypertension, taking all BP-lowering drugs at bedtime vs in the morning reduced CV events

Paul Glasziou*, Jenny Doust

*Corresponding author for this work

Research output: Contribution to journalComment/debateResearchpeer-review

Abstract

GIM/FP/GP:
Cardiology:
In adults with hypertension, does taking all blood pressure (BP)–lowering drugs at bedtime vs on awakening in the morning reduce cardiovascular (CV) events?
Randomized controlled trial (RCT) (Hygia Chronotherapy Trial).
Treatment allocation concealment unclear; blinded (outcome adjudication committee).*
40 primary care centers in Galicia, Spain.
19 168 patients ≥ 18 years of age (mean age 61 y, 56% men) who had hypertension confirmed by 48-hour ambulatory BP monitoring (mean awake...
Original languageEnglish
Pages (from-to)JC29-JC29
Number of pages1
JournalAnnals of Internal Medicine
Volume172
Issue number6
DOIs
Publication statusPublished - 17 Mar 2020

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