High throughput and wide field of view EUV microscope for blur-free one-shot imaging of living organisms

Takeo Ejima, Fumihiko Ishida, Hiromichi Murata, Mitsunori Toyoda, Tetsuo Harada, Toshihide Tsuru, Tadashi Hatano, Mihiro Yanagihara, Masaki Yamamoto, Haruo Mizutani

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Abstract

We present and demonstrate the use of an extreme ultraviolet (EUV) microscope that was developed in-house. Images are acquired using Bragg reflection multilayer optics and a laser-produced plasma light source. The upper-limit spatial resolution of the EUV microscope is 130 nm with a 10 ns exposure time and 250 x 250 μm2 field of view. Resolution is superior to that of visible microscopes with the same size of field of view, and the exposure time is short enough to observe fine structures in-vivo. Observation of the cerebral cortex of a mouse is demonstrated.

Original languageEnglish
Pages (from-to)7203-7209
Number of pages7
JournalOptics Express
Volume18
Issue number7
DOIs
Publication statusPublished - 29 Mar 2010
Externally publishedYes

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organisms
shot
field of view
microscopes
cerebral cortex
laser plasmas
mice
light sources
spatial resolution
fine structure
optics

Cite this

Ejima, T., Ishida, F., Murata, H., Toyoda, M., Harada, T., Tsuru, T., ... Mizutani, H. (2010). High throughput and wide field of view EUV microscope for blur-free one-shot imaging of living organisms. Optics Express, 18(7), 7203-7209. https://doi.org/10.1364/OE.18.007203
Ejima, Takeo ; Ishida, Fumihiko ; Murata, Hiromichi ; Toyoda, Mitsunori ; Harada, Tetsuo ; Tsuru, Toshihide ; Hatano, Tadashi ; Yanagihara, Mihiro ; Yamamoto, Masaki ; Mizutani, Haruo. / High throughput and wide field of view EUV microscope for blur-free one-shot imaging of living organisms. In: Optics Express. 2010 ; Vol. 18, No. 7. pp. 7203-7209.
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Ejima, T, Ishida, F, Murata, H, Toyoda, M, Harada, T, Tsuru, T, Hatano, T, Yanagihara, M, Yamamoto, M & Mizutani, H 2010, 'High throughput and wide field of view EUV microscope for blur-free one-shot imaging of living organisms' Optics Express, vol. 18, no. 7, pp. 7203-7209. https://doi.org/10.1364/OE.18.007203

High throughput and wide field of view EUV microscope for blur-free one-shot imaging of living organisms. / Ejima, Takeo; Ishida, Fumihiko; Murata, Hiromichi; Toyoda, Mitsunori; Harada, Tetsuo; Tsuru, Toshihide; Hatano, Tadashi; Yanagihara, Mihiro; Yamamoto, Masaki; Mizutani, Haruo.

In: Optics Express, Vol. 18, No. 7, 29.03.2010, p. 7203-7209.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Harada, Tetsuo

AU - Tsuru, Toshihide

AU - Hatano, Tadashi

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AU - Yamamoto, Masaki

AU - Mizutani, Haruo

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