Heterogeneity among H-2Kk antigens. Differential expression on lymphoid cells

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Abstract

Evidence is presented for heterogeneity in the expression of H-2Kk determinants specific for two monoclonal antibodies, H100-30.R3 and 11-4.1. Heterogeneity was detectable by differences in cellular distribution on thymocytes and activated T cells, but not by sequential immunoprecipitation or differential redistribution studies. This result contrasts with earlier evidence of heterogeneity, demonstrable by these latter methods, between H-2Kk determinants specific for H100-30.R3 and another antibody, H100-27.R9.

Original languageEnglish
Pages (from-to)182-188
Number of pages7
JournalTransplantation
Volume38
Issue number2
Publication statusPublished - Aug 1984
Externally publishedYes

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Thymocytes
Immunoprecipitation
Monoclonal Antibodies
Lymphocytes
T-Lymphocytes
Antibodies
H antigen

Cite this

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title = "Heterogeneity among H-2Kk antigens. Differential expression on lymphoid cells",
abstract = "Evidence is presented for heterogeneity in the expression of H-2Kk determinants specific for two monoclonal antibodies, H100-30.R3 and 11-4.1. Heterogeneity was detectable by differences in cellular distribution on thymocytes and activated T cells, but not by sequential immunoprecipitation or differential redistribution studies. This result contrasts with earlier evidence of heterogeneity, demonstrable by these latter methods, between H-2Kk determinants specific for H100-30.R3 and another antibody, H100-27.R9.",
author = "O'Neill, {H C}",
year = "1984",
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language = "English",
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}

Heterogeneity among H-2Kk antigens. Differential expression on lymphoid cells. / O'Neill, H C.

In: Transplantation, Vol. 38, No. 2, 08.1984, p. 182-188.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Heterogeneity among H-2Kk antigens. Differential expression on lymphoid cells

AU - O'Neill, H C

PY - 1984/8

Y1 - 1984/8

N2 - Evidence is presented for heterogeneity in the expression of H-2Kk determinants specific for two monoclonal antibodies, H100-30.R3 and 11-4.1. Heterogeneity was detectable by differences in cellular distribution on thymocytes and activated T cells, but not by sequential immunoprecipitation or differential redistribution studies. This result contrasts with earlier evidence of heterogeneity, demonstrable by these latter methods, between H-2Kk determinants specific for H100-30.R3 and another antibody, H100-27.R9.

AB - Evidence is presented for heterogeneity in the expression of H-2Kk determinants specific for two monoclonal antibodies, H100-30.R3 and 11-4.1. Heterogeneity was detectable by differences in cellular distribution on thymocytes and activated T cells, but not by sequential immunoprecipitation or differential redistribution studies. This result contrasts with earlier evidence of heterogeneity, demonstrable by these latter methods, between H-2Kk determinants specific for H100-30.R3 and another antibody, H100-27.R9.

M3 - Article

VL - 38

SP - 182

EP - 188

JO - Transplantation bulletin

JF - Transplantation bulletin

SN - 0041-1337

IS - 2

ER -