Abstract
The increasing use of herbal medicinal products (HMPs) in the community where people are also receiving prescription medicines suggests that adverse herb-drug interactions may be of significant public health consequence. The evidence available to guide practitioners in decision making is complex and consists of a range of sources including adverse event database entries, spontaneous or case reports, in vivo and in vitro drug metabolism studies, and in vivo drug interaction studies in healthy subjects and patients. In the absence of further rigorous studies to assess the clinical significance of herb-drug interactions, an evidence-based appraisal of the current literature is essential to guide practitioners involved in patient care.
| Original language | English |
|---|---|
| Pages (from-to) | 1513-1525 |
| Number of pages | 13 |
| Journal | Current Medicinal Chemistry |
| Volume | 11 |
| Issue number | 11 |
| Publication status | Published - Jun 2004 |
| Externally published | Yes |
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Herb-drug interactions : An evidence based approach. / Coxeter, P. D.; McLachlan, Andrew J; Duke, C. C.; Roufogalis, B. D.
In: Current Medicinal Chemistry, Vol. 11, No. 11, 06.2004, p. 1513-1525.Research output: Contribution to journal › Review article › Research › peer-review
TY - JOUR
T1 - Herb-drug interactions
T2 - An evidence based approach
AU - Coxeter, P. D.
AU - McLachlan, Andrew J
AU - Duke, C. C.
AU - Roufogalis, B. D.
PY - 2004/6
Y1 - 2004/6
N2 - The increasing use of herbal medicinal products (HMPs) in the community where people are also receiving prescription medicines suggests that adverse herb-drug interactions may be of significant public health consequence. The evidence available to guide practitioners in decision making is complex and consists of a range of sources including adverse event database entries, spontaneous or case reports, in vivo and in vitro drug metabolism studies, and in vivo drug interaction studies in healthy subjects and patients. In the absence of further rigorous studies to assess the clinical significance of herb-drug interactions, an evidence-based appraisal of the current literature is essential to guide practitioners involved in patient care.
AB - The increasing use of herbal medicinal products (HMPs) in the community where people are also receiving prescription medicines suggests that adverse herb-drug interactions may be of significant public health consequence. The evidence available to guide practitioners in decision making is complex and consists of a range of sources including adverse event database entries, spontaneous or case reports, in vivo and in vitro drug metabolism studies, and in vivo drug interaction studies in healthy subjects and patients. In the absence of further rigorous studies to assess the clinical significance of herb-drug interactions, an evidence-based appraisal of the current literature is essential to guide practitioners involved in patient care.
UR - http://www.scopus.com/inward/record.url?scp=2942568114&partnerID=8YFLogxK
M3 - Review article
VL - 11
SP - 1513
EP - 1525
JO - Current Medicinal Chemistry
JF - Current Medicinal Chemistry
SN - 0929-8673
IS - 11
ER -