Herb-drug interactions: An evidence based approach

P. D. Coxeter, Andrew J McLachlan, C. C. Duke, B. D. Roufogalis

Research output: Contribution to journalReview articleResearchpeer-review

51 Citations (Scopus)

Abstract

The increasing use of herbal medicinal products (HMPs) in the community where people are also receiving prescription medicines suggests that adverse herb-drug interactions may be of significant public health consequence. The evidence available to guide practitioners in decision making is complex and consists of a range of sources including adverse event database entries, spontaneous or case reports, in vivo and in vitro drug metabolism studies, and in vivo drug interaction studies in healthy subjects and patients. In the absence of further rigorous studies to assess the clinical significance of herb-drug interactions, an evidence-based appraisal of the current literature is essential to guide practitioners involved in patient care.

Original languageEnglish
Pages (from-to)1513-1525
Number of pages13
JournalCurrent Medicinal Chemistry
Volume11
Issue number11
Publication statusPublished - Jun 2004
Externally publishedYes

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Herb-Drug Interactions
Drug interactions
Drug Interactions
Prescriptions
Decision Making
Patient Care
Healthy Volunteers
Public Health
Public health
Databases
Metabolism
Decision making
Pharmaceutical Preparations

Cite this

Coxeter, P. D., McLachlan, A. J., Duke, C. C., & Roufogalis, B. D. (2004). Herb-drug interactions: An evidence based approach. Current Medicinal Chemistry, 11(11), 1513-1525.
Coxeter, P. D. ; McLachlan, Andrew J ; Duke, C. C. ; Roufogalis, B. D. / Herb-drug interactions : An evidence based approach. In: Current Medicinal Chemistry. 2004 ; Vol. 11, No. 11. pp. 1513-1525.
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Coxeter, PD, McLachlan, AJ, Duke, CC & Roufogalis, BD 2004, 'Herb-drug interactions: An evidence based approach' Current Medicinal Chemistry, vol. 11, no. 11, pp. 1513-1525.

Herb-drug interactions : An evidence based approach. / Coxeter, P. D.; McLachlan, Andrew J; Duke, C. C.; Roufogalis, B. D.

In: Current Medicinal Chemistry, Vol. 11, No. 11, 06.2004, p. 1513-1525.

Research output: Contribution to journalReview articleResearchpeer-review

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Coxeter PD, McLachlan AJ, Duke CC, Roufogalis BD. Herb-drug interactions: An evidence based approach. Current Medicinal Chemistry. 2004 Jun;11(11):1513-1525.