TY - JOUR
T1 - Gastric Emptying in the Elderly
AU - Soenen, Stijn
AU - Rayner, Chris K.
AU - Horowitz, Michael
AU - Jones, Karen L.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Aging is characterized by a diminished homeostatic regulation of physiologic functions, including slowing of gastric emptying. Gastric and small intestinal motor and humoral mechanisms in humans are complex and highly variable: ingested food is stored, mixed with digestive enzymes, ground into small particles, and delivered as a liquefied form into the duodenum at a rate allowing efficient digestion and absorption. In healthy aging, motor function is well preserved whereas deficits in sensory function are more apparent. The effects of aging on gastric emptying are relevant to the absorption of oral medications and the regulation of appetite, postprandial glycemia, and blood pressure.
AB - Aging is characterized by a diminished homeostatic regulation of physiologic functions, including slowing of gastric emptying. Gastric and small intestinal motor and humoral mechanisms in humans are complex and highly variable: ingested food is stored, mixed with digestive enzymes, ground into small particles, and delivered as a liquefied form into the duodenum at a rate allowing efficient digestion and absorption. In healthy aging, motor function is well preserved whereas deficits in sensory function are more apparent. The effects of aging on gastric emptying are relevant to the absorption of oral medications and the regulation of appetite, postprandial glycemia, and blood pressure.
UR - http://www.scopus.com/inward/record.url?scp=84945469169&partnerID=8YFLogxK
U2 - 10.1016/j.cger.2015.04.003
DO - 10.1016/j.cger.2015.04.003
M3 - Review article
C2 - 26195094
AN - SCOPUS:84945469169
SN - 0749-0690
VL - 31
SP - 339
EP - 353
JO - Clinics in Geriatric Medicine
JF - Clinics in Geriatric Medicine
IS - 3
ER -