Folate degradation due to ultraviolet radiation: Possible implications for human health and nutrition

David C. Borradale*, Michael G. Kimlin

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Abstract

Folate is essential for human health in the prevention of megaloblastic anemia and neural tube birth defects and plays important roles in cardiovascular disease and cancer. Therefore, research into environmental factors that may impact folate status, such as solar ultraviolet (UV) radiation, is of great health significance. In vitro studies have shown that UV radiation can degrade folate and folic acid in human blood and this has been confirmed in several human studies. Despite these findings, there is a dearth of epidemiological research into investigating the relationship between folate status and the links to solar UV exposure.

Original languageEnglish
Pages (from-to)414-422
Number of pages9
JournalNutrition Reviews
Volume70
Issue number7
DOIs
Publication statusPublished - Jul 2012
Externally publishedYes

Fingerprint

Dive into the research topics of 'Folate degradation due to ultraviolet radiation: Possible implications for human health and nutrition'. Together they form a unique fingerprint.

Cite this