Abstract
Pregnancy places a high nutritional demand on the mother. Opportunistic learnings from the Dutch famine of 1944-45 have provided information about the long-term effects of prenatal undernutrition.
Most notably, exposure to famine (daily diets restricted to below 1000 calories during any 13-week period) at any stage during pregnancy was associated with adverse health outcomes in the offspring, including low birth weight and an increased risk of metabolic disorders later in life. These data also highlight differences in placentation, the placenta was less efficient in mothers exposed to famine during the mid-late gestational periods than were those exposed during early gestation.
Most notably, exposure to famine (daily diets restricted to below 1000 calories during any 13-week period) at any stage during pregnancy was associated with adverse health outcomes in the offspring, including low birth weight and an increased risk of metabolic disorders later in life. These data also highlight differences in placentation, the placenta was less efficient in mothers exposed to famine during the mid-late gestational periods than were those exposed during early gestation.
| Original language | English |
|---|---|
| Pages | 74-80 |
| Number of pages | 16 |
| No. | 5 |
| Specialist publication | AJP: The Australian Journal of Pharmacy |
| Publication status | Published - 31 May 2024 |
