Ethical priorities for international collaborative adaptive platform trials for public health emergencies

Katharine Wright, Joseph Ali, Alun Davies, Paul Glasziou, Nina Gobat, Tanja Kuchenmüller, Katherine Littler, Chelsea Modlin, Lee-Anne Pascoe, Andreas Reis, Jerome Amir Singh

Research output: Contribution to journalComment/debate/opinionResearchpeer-review

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Abstract

Rapidly produced evidence on effective medical counter measures is critical for responding to health emergencies caused by (re-)emerging infectious diseases.

Adaptive platform trials played a significant role in the global research response to COVID-19 and are likely to be increasingly used in the future, both in emergency and non-emergency contexts.

We call attention to a number of ethical considerations that should influence the development and future implementation of large-scale multicountry adaptive platform studies.
Original languageEnglish
Article numbere012930
Pages (from-to)1-4
Number of pages4
JournalBMJ Global Health
Volume8
Issue number7
DOIs
Publication statusPublished - 31 Jul 2023

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