Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells

Kylie Mills; Catherine McDermott; Russ Chess-Williams

Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells

Kylie Mills, Catherine McDermott, Russ Chess-Williams

Research output: Contribution to conference › Abstract › Research › peer-review

Abstract

Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.

Original language	English
Pages	206-206
Number of pages	1
Publication status	Published - 2012
Event	Joint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia Duration: 2 Dec 2012 → 5 Dec 2012 http://www.ascept-apsa.com/

Conference

Conference	Joint ASCEPT- APSA 2012 Conference
Country/Territory	Australia
City	Sydney
Period	2/12/12 → 5/12/12
Internet address	http://www.ascept-apsa.com/

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http://www.ascept-apsa.com/wp-content/uploads/2012/07/ASCEPT-APSA-Poster-Abstracts-570-644.pdf

Cyclophosphamide and ifosfamide: mechanisms of cytotoxic action and consequences for normal bladder function
Mills, K. (Author), Chess-Williams, R. G. (Supervisor) & McDermott, C. (Supervisor), 10 Oct 2015
Student thesis: Doctoral Thesis

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Mills, K., McDermott, C., & Chess-Williams, R. (2012). Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells. 206-206. Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia. http://www.ascept-apsa.com/wp-content/uploads/2012/07/ASCEPT-APSA-Poster-Abstracts-570-644.pdf

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title = "Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells",

abstract = "Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.",

author = "Kylie Mills and Catherine McDermott and Russ Chess-Williams",

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Mills, K, McDermott, C & Chess-Williams, R 2012, 'Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells', Joint ASCEPT- APSA 2012 Conference , Sydney, Australia, 2/12/12 - 5/12/12 pp. 206-206. <http://www.ascept-apsa.com/wp-content/uploads/2012/07/ASCEPT-APSA-Poster-Abstracts-570-644.pdf >

TY - CONF

T1 - Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells

AU - Mills, Kylie

AU - McDermott, Catherine

AU - Chess-Williams, Russ

PY - 2012

Y1 - 2012

N2 - Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.

AB - Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.

M3 - Abstract

SP - 206

EP - 206

T2 - Joint ASCEPT- APSA 2012 Conference

Y2 - 2 December 2012 through 5 December 2012

ER -

Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells

Abstract

Conference

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Student theses

Cyclophosphamide and ifosfamide: mechanisms of cytotoxic action and consequences for normal bladder function

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