Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.
|Number of pages||1|
|Publication status||Published - 2012|
|Event||Joint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia|
Duration: 2 Dec 2012 → 5 Dec 2012
|Conference||Joint ASCEPT- APSA 2012 Conference|
|Period||2/12/12 → 5/12/12|
Mills, K., McDermott, C., & Chess-Williams, R. (2012). Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells. 206-206. Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia.