Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells

Research output: Contribution to conferenceAbstractResearchpeer-review

Abstract

Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.
Original languageEnglish
Pages206-206
Number of pages1
Publication statusPublished - 2012
EventJoint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia
Duration: 2 Dec 20125 Dec 2012
http://www.ascept-apsa.com/

Conference

ConferenceJoint ASCEPT- APSA 2012 Conference
CountryAustralia
CitySydney
Period2/12/125/12/12
Internet address

Fingerprint

Acrolein
Urothelium
Ifosfamide
Cyclophosphamide
Urinary Bladder
Dysuria
Antineoplastic Agents
Urine
Pain
Pharmaceutical Preparations

Cite this

Mills, K., McDermott, C., & Chess-Williams, R. (2012). Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells. 206-206. Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia.
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abstract = "Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.",
author = "Kylie Mills and Catherine McDermott and Russ Chess-Williams",
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note = "Joint ASCEPT- APSA 2012 Conference : Medication Safety ; Conference date: 02-12-2012 Through 05-12-2012",
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}

Mills, K, McDermott, C & Chess-Williams, R 2012, 'Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells' Joint ASCEPT- APSA 2012 Conference , Sydney, Australia, 2/12/12 - 5/12/12, pp. 206-206.

Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells. / Mills, Kylie; McDermott, Catherine; Chess-Williams, Russ.

2012. 206-206 Abstract from Joint ASCEPT- APSA 2012 Conference , Sydney, Australia.

Research output: Contribution to conferenceAbstractResearchpeer-review

TY - CONF

T1 - Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells

AU - Mills, Kylie

AU - McDermott, Catherine

AU - Chess-Williams, Russ

PY - 2012

Y1 - 2012

N2 - Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.

AB - Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.

M3 - Abstract

SP - 206

EP - 206

ER -