Effects of acrolein, a metabolite of Cyclophosphamide and Ifosfamide, on cultured human urothelial cells

Research output: Contribution to conferenceAbstractResearchpeer-review

Abstract

Cyclophosphamide and ifosfamide are commonly used anticancer agents. A major limiting factor in their use is the resulting bladder toxicity which can result in ongoing bladder pain, urgency and dysuria. These drugs and their metabolites come into contact with the urothelium when they are excreted in the urine, potentially damaging the urothelium.
Original languageEnglish
Pages206-206
Number of pages1
Publication statusPublished - 2012
EventJoint ASCEPT- APSA 2012 Conference : Medication Safety - Sydney Convention and Exhibition Centre, Sydney, Australia
Duration: 2 Dec 20125 Dec 2012
http://www.ascept-apsa.com/

Conference

ConferenceJoint ASCEPT- APSA 2012 Conference
CountryAustralia
CitySydney
Period2/12/125/12/12
Internet address

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  • Student Theses

    Cyclophosphamide and ifosfamide: mechanisms of cytotoxic action and consequences for normal bladder function

    Author: Mills, K., 10 Oct 2015

    Supervisor: Chess-Williams, R. G. (Supervisor) & McDermott, C. (Supervisor)

    Student thesis: Doctoral Thesis

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