Effect of different protocols of caffeine intake on metabolism and endurance performance

Gregory R. Cox, Ben Desbrow, Paul G. Montgomery, Megan E. Anderson, Clinton R. Bruce, Theodore A. Macrides, David T. Martin, Angela Moquin, Alan Roberts, John A. Hawley, Louise M. Burke

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180 Citations (Scopus)

Abstract

Competitive athletes completed two studies of 2-h steady-state (SS) cycling at 70% peak O2 uptake followed by 7 kJ/kg time trial (TT) with carbohydrate (CHO) intake before (2 g/kg) and during (6% CHO drink) exercise. In Study A, 12 subjects received either 6 mg/kg caffeine 1 h preexercise (Precaf), 6 × 1 mg/kg caffeine every 20 min throughout SS (Durcaf), 2 × 5 ml/kg Coca-Cola between 100 and 120 min SS and during TT (Coke), or placebo. Improvements in TT were as follows: Precaf, 3.4% (0.2-6.5%, 95% confidence interval); Durcaf, 3.1% (-0.1-6.5%); and Coke, 3.1% (-0.2-6.2%). In Study B, eight subjects received 3 × 5 ml/kg of different cola drinks during the last 40 min of SS and TT: decaffeinated, 6% CHO (control); caffeinated, 6% CHO; decaffeinated, 11% CHO; and caffeinated, 11% CHO (Coke). Coke enhanced TT by 3.3% (0.8-5.9%), with all trials showing 2.2% TT enhancement (0.5-3.8%; P < 0.05) due to caffeine. Overall, 1) 6 mg/kg caffeine enhanced TT performance independent of timing of intake and 2) replacing sports drink with Coca-Cola during the latter stages of exercise was equally effective in enhancing endurance performance, primarily due to low intake of caffeine (∼1.5 mg/kg).

Original languageEnglish
Pages (from-to)990-999
Number of pages10
JournalJournal of Applied Physiology
Volume93
Issue number3
DOIs
Publication statusPublished - 1 Jan 2002
Externally publishedYes

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Caffeine
Coke
Exercise
Athletes
Sports
Placebos
Carbohydrates
Confidence Intervals

Cite this

Cox, G. R., Desbrow, B., Montgomery, P. G., Anderson, M. E., Bruce, C. R., Macrides, T. A., ... Burke, L. M. (2002). Effect of different protocols of caffeine intake on metabolism and endurance performance. Journal of Applied Physiology, 93(3), 990-999. https://doi.org/10.1152/japplphysiol.00249.2002
Cox, Gregory R. ; Desbrow, Ben ; Montgomery, Paul G. ; Anderson, Megan E. ; Bruce, Clinton R. ; Macrides, Theodore A. ; Martin, David T. ; Moquin, Angela ; Roberts, Alan ; Hawley, John A. ; Burke, Louise M. / Effect of different protocols of caffeine intake on metabolism and endurance performance. In: Journal of Applied Physiology. 2002 ; Vol. 93, No. 3. pp. 990-999.
@article{0b7965ba14764751a74c619c0b02e70b,
title = "Effect of different protocols of caffeine intake on metabolism and endurance performance",
abstract = "Competitive athletes completed two studies of 2-h steady-state (SS) cycling at 70{\%} peak O2 uptake followed by 7 kJ/kg time trial (TT) with carbohydrate (CHO) intake before (2 g/kg) and during (6{\%} CHO drink) exercise. In Study A, 12 subjects received either 6 mg/kg caffeine 1 h preexercise (Precaf), 6 × 1 mg/kg caffeine every 20 min throughout SS (Durcaf), 2 × 5 ml/kg Coca-Cola between 100 and 120 min SS and during TT (Coke), or placebo. Improvements in TT were as follows: Precaf, 3.4{\%} (0.2-6.5{\%}, 95{\%} confidence interval); Durcaf, 3.1{\%} (-0.1-6.5{\%}); and Coke, 3.1{\%} (-0.2-6.2{\%}). In Study B, eight subjects received 3 × 5 ml/kg of different cola drinks during the last 40 min of SS and TT: decaffeinated, 6{\%} CHO (control); caffeinated, 6{\%} CHO; decaffeinated, 11{\%} CHO; and caffeinated, 11{\%} CHO (Coke). Coke enhanced TT by 3.3{\%} (0.8-5.9{\%}), with all trials showing 2.2{\%} TT enhancement (0.5-3.8{\%}; P < 0.05) due to caffeine. Overall, 1) 6 mg/kg caffeine enhanced TT performance independent of timing of intake and 2) replacing sports drink with Coca-Cola during the latter stages of exercise was equally effective in enhancing endurance performance, primarily due to low intake of caffeine (∼1.5 mg/kg).",
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Cox, GR, Desbrow, B, Montgomery, PG, Anderson, ME, Bruce, CR, Macrides, TA, Martin, DT, Moquin, A, Roberts, A, Hawley, JA & Burke, LM 2002, 'Effect of different protocols of caffeine intake on metabolism and endurance performance' Journal of Applied Physiology, vol. 93, no. 3, pp. 990-999. https://doi.org/10.1152/japplphysiol.00249.2002

Effect of different protocols of caffeine intake on metabolism and endurance performance. / Cox, Gregory R.; Desbrow, Ben; Montgomery, Paul G.; Anderson, Megan E.; Bruce, Clinton R.; Macrides, Theodore A.; Martin, David T.; Moquin, Angela; Roberts, Alan; Hawley, John A.; Burke, Louise M.

In: Journal of Applied Physiology, Vol. 93, No. 3, 01.01.2002, p. 990-999.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Desbrow, Ben

AU - Montgomery, Paul G.

AU - Anderson, Megan E.

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AU - Macrides, Theodore A.

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AU - Burke, Louise M.

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