Does milk cause constipation? A crossover dietary trial

Elesa T. Crowley, Lauren T. Williams, Tim K. Roberts, Richard H. Dunstan, Peter D. Jones

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Abstract

The aims of this study were to: (1) determine whether replacement of cow's milk protein with soy resolves Chronic Functional Constipation (CFC); and (2) investigate the effects of cow's milk β casein A1 and cow's milk β casein A2 on CFC. Children diagnosed with CFC were recruited to one of two crossover trials: Trial 1 compared the effects of cow's milk and soy milk; Trial 2 compared the effects of cow's milk β casein A1 and cow's milk β casein A2. Resolution of constipation was defined as greater than eight bowel motions during a two week intervention. Thirteen children (18 to 144 months) participated in Trial 1 (6 boys, 7 girls). Nine participants who completed the soy epoch all experienced resolution (p < 0.05). Thirty-nine children (21 to 144 months) participated in Trial 2 (25 boys, 14 girls). Resolution of constipation was highest during the washout epoch, 81%; followed by cow's milk β casein A2, 79%; and cow's milk β casein A1, 57%; however, the proportions did not differ statistically. The results of Trial 1 demonstrate an association between CFC and cow's milk consumption but Trial 2 failed to show an effect from type of casein. Some other component in cow's milk common to both A1 and A2 milk may be causing a problem in these susceptible children.

Original languageEnglish
Pages (from-to)253-266
Number of pages14
JournalNutrients
Volume5
Issue number1
DOIs
Publication statusPublished - 22 Jan 2013

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constipation
Constipation
Cross-Over Studies
Milk
Caseins
milk
casein
varespladib methyl
Soy Milk
soymilk
milk consumption
Milk Proteins
dairy protein
cows

Cite this

Crowley, E. T., Williams, L. T., Roberts, T. K., Dunstan, R. H., & Jones, P. D. (2013). Does milk cause constipation? A crossover dietary trial. Nutrients, 5(1), 253-266. https://doi.org/10.3390/nu5010253
Crowley, Elesa T. ; Williams, Lauren T. ; Roberts, Tim K. ; Dunstan, Richard H. ; Jones, Peter D. / Does milk cause constipation? A crossover dietary trial. In: Nutrients. 2013 ; Vol. 5, No. 1. pp. 253-266.
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Crowley, ET, Williams, LT, Roberts, TK, Dunstan, RH & Jones, PD 2013, 'Does milk cause constipation? A crossover dietary trial', Nutrients, vol. 5, no. 1, pp. 253-266. https://doi.org/10.3390/nu5010253

Does milk cause constipation? A crossover dietary trial. / Crowley, Elesa T.; Williams, Lauren T.; Roberts, Tim K.; Dunstan, Richard H.; Jones, Peter D.

In: Nutrients, Vol. 5, No. 1, 22.01.2013, p. 253-266.

Research output: Contribution to journalArticleResearchpeer-review

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Crowley ET, Williams LT, Roberts TK, Dunstan RH, Jones PD. Does milk cause constipation? A crossover dietary trial. Nutrients. 2013 Jan 22;5(1):253-266. https://doi.org/10.3390/nu5010253