Do SmartSite antireflux valves limit the flow rate of 0.9% normal saline through intravenous cannulas?

David Liu, Gerben Keijzers

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)


The aim of the study was to determine whether the placement of a SmartSite antireflux valve between a bag of fluid with line giving set and an intravenous cannula decreases the flow rate. Fluid flow rates were compared in paired experiments with and without an antireflux valve using a pressure infuser or allowing fluid to flow by gravity only for four different sizes of intravenous cannulas (20-14 G). Antireflux valves significantly decreased the fluid flow rates for all cannula sizes, irrespective of whether a pressure infuser was used. The decrease in the flow rate was most marked for larger cannulas [gravity only: 14 G: 52% (95% confidence interval (CI): 37-68), 16 G: 39% (95% CI: 34-43); pressure bag: 14 G: 74% (95% CI: 70-78), 16 G: 56% (95% CI: 54-57); all P<0.001]. Where maximum fluid flow rates are desirable, clinicians should consider not using an antireflux valve.

Original languageEnglish
Pages (from-to)123-5
Number of pages3
JournalEuropean Journal of Emergency Medicine
Issue number2
Publication statusPublished - Apr 2013


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