DARPP-32 like protein in specific snail (Helix aspersa) neurones

N. N. Osborne, N. L. Barnett, N. J. Morris

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

Monoclonal antibodies to DARPP-32 recognise an antigen which is present in specific neurones in the snail (Helix aspersa). Consecutive sections 10-μm-thick processed for the localisation of DARPP-32 and tyrosine-hydroxylase immunoreactivity did not show a coexistence in any neuronal structures. DARPP-32 positive cells were, however, often morphologically closely associated with tyrosine-hydroxylase positive cells, implying a functional relationship consistent with the proposed role of DARPP-32. Immunochemical analysis of the DARPP-32 immunoreative material in the snail nervous system shows that the substance has a molecular weight of 28 kDa and therefore different from the DARPP-32 protein found in the rat brain.

Original languageEnglish
Pages (from-to)413-417
Number of pages5
JournalHistochemistry
Volume95
Issue number4
DOIs
Publication statusPublished - 1 Feb 1991
Externally publishedYes

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tyrosine 3-monooxygenase
Dopamine and cAMP-Regulated Phosphoprotein 32
Helix (Snails)
Helix aspersa
Tyrosine 3-Monooxygenase
snails
neurons
Neurons
Snails
nervous system
Nervous System
monoclonal antibodies
proteins
Molecular Weight
Monoclonal Antibodies
cells
molecular weight
antigens
brain
Antigens

Cite this

Osborne, N. N. ; Barnett, N. L. ; Morris, N. J. / DARPP-32 like protein in specific snail (Helix aspersa) neurones. In: Histochemistry. 1991 ; Vol. 95, No. 4. pp. 413-417.
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DARPP-32 like protein in specific snail (Helix aspersa) neurones. / Osborne, N. N.; Barnett, N. L.; Morris, N. J.

In: Histochemistry, Vol. 95, No. 4, 01.02.1991, p. 413-417.

Research output: Contribution to journalReview articleResearchpeer-review

TY - JOUR

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AU - Morris, N. J.

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