TY - JOUR
T1 - Cytokine profiles and salivary IgA and hormonal responses to an acute bout of strenuous endurance exercise
AU - Kakanis, Michael
AU - Peake, Jonathan
AU - Brenu, Ekua
AU - Hooper, Sue
AU - Gray, Athol Bon
AU - Marshall-Gradisnik, Sonya
PY - 2011/12
Y1 - 2011/12
N2 - Introduction: Strenuous endurance exercise suppresses some immune variables such as T helper (Th) cell activities during the post-exercise recovery period. Changes in the Th1/Th2 response to exercise have been reported previously; however, earlier reports have not investigated cytokine production by phytohemagglutinin (PHA)-stimulated Th cells following strenuous endurance exercise. Changes in plasma cortisol and salivary IgA concentrations have been linked to the exercise-induced immunosuppression explained by the ‘open window’ theory. This study measured the production of cytokines by Th1/Th2/Th17 cells, salivary IgA concentration and plasma cortisol concentration for 8 h following an acute bout of strenuous endurance exercise.
AB - Introduction: Strenuous endurance exercise suppresses some immune variables such as T helper (Th) cell activities during the post-exercise recovery period. Changes in the Th1/Th2 response to exercise have been reported previously; however, earlier reports have not investigated cytokine production by phytohemagglutinin (PHA)-stimulated Th cells following strenuous endurance exercise. Changes in plasma cortisol and salivary IgA concentrations have been linked to the exercise-induced immunosuppression explained by the ‘open window’ theory. This study measured the production of cytokines by Th1/Th2/Th17 cells, salivary IgA concentration and plasma cortisol concentration for 8 h following an acute bout of strenuous endurance exercise.
U2 - 10.1016/j.jsams.2011.11.208
DO - 10.1016/j.jsams.2011.11.208
M3 - Meeting Abstract
SN - 1440-2440
VL - 14
SP - e99-e100
JO - Journal of Science and Medicine in Sport
JF - Journal of Science and Medicine in Sport
IS - Supp 1
M1 - 206
ER -