Introduction: Strenuous endurance exercise suppresses some immune variables such as T helper (Th) cell activities during the post-exercise recovery period. Changes in the Th1/Th2 response to exercise have been reported previously; however, earlier reports have not investigated cytokine production by phytohemagglutinin (PHA)-stimulated Th cells following strenuous endurance exercise. Changes in plasma cortisol and salivary IgA concentrations have been linked to the exercise-induced immunosuppression explained by the ‘open window’ theory. This study measured the production of cytokines by Th1/Th2/Th17 cells, salivary IgA concentration and plasma cortisol concentration for 8 h following an acute bout of strenuous endurance exercise.
Kakanis, M., Peake, J., Brenu, E., Hooper, S., Gray, A. B., & Marshall-Gradisnik, S. (2011). Cytokine profiles and salivary IgA and hormonal responses to an acute bout of strenuous endurance exercise. Journal of Science and Medicine in Sport, 14(Supp 1), e99-e100. . https://doi.org/10.1016/j.jsams.2011.11.208