Cytokine profiles and salivary IgA and hormonal responses to an acute bout of strenuous endurance exercise

Michael Kakanis, Jonathan Peake, Ekua Brenu, Sue Hooper, Athol Bon Gray, Sonya Marshall-Gradisnik

Research output: Contribution to journalMeeting AbstractResearchpeer-review


Introduction: Strenuous endurance exercise suppresses some immune variables such as T helper (Th) cell activities during the post-exercise recovery period. Changes in the Th1/Th2 response to exercise have been reported previously; however, earlier reports have not investigated cytokine production by phytohemagglutinin (PHA)-stimulated Th cells following strenuous endurance exercise. Changes in plasma cortisol and salivary IgA concentrations have been linked to the exercise-induced immunosuppression explained by the ‘open window’ theory. This study measured the production of cytokines by Th1/Th2/Th17 cells, salivary IgA concentration and plasma cortisol concentration for 8 h following an acute bout of strenuous endurance exercise.
Original languageEnglish
Article number206
Pages (from-to)e99-e100
Number of pages2
JournalJournal of Science and Medicine in Sport
Issue numberSupp 1
Publication statusPublished - Dec 2011


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