TY - JOUR
T1 - Consensus guidelines for sarcopenia prevention, diagnosis and management in Australia and New Zealand
AU - Zanker, Jesse
AU - Sim, Marc
AU - Anderson, Kate
AU - Balogun, Saliu
AU - Brennan-Olsen, Sharon L
AU - Dent, Elsa
AU - Duque, Gustavo
AU - Girgis, Christian M
AU - Grossmann, Mathis
AU - Hayes, Alan
AU - Henwood, Tim
AU - Hirani, Vasant
AU - Inderjeeth, Charles
AU - Iuliano, Sandra
AU - Keogh, Justin
AU - Lewis, Josh
AU - Lynch, Gordon S
AU - Pasco, Julie A
AU - Phu, Steven
AU - Reijnierse, Esmee M
AU - Russell, Nicholas
AU - Vlietstra, Lara
AU - Visvanathan, Renuka
AU - Walker, Troy
AU - Waters, Debra L
AU - Yu, Solomon
AU - Maier, Andrea B
AU - Daly, Robin M
AU - Scott, David
N1 - © 2022 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.
Funding Information:
ABM has received speaker and consulting fees from Abbott, Nutricia, AstraZeneca, Novartis. GD is a member of the Scientific Advisory Board of TSI, Abbott and Amgen and has received speaker/consulting fees from Amgen, Abbott and TSI. MG has received research funding from Bayer Pharma, Novartis, Weight Watchers, Lilly, Otsuka and speaker's honoraria from Bayer Pharma, Besins Healthcare, and Amgen. RMD reports a grant form Fonterra Co‐operative Group Ltd, honoraria for presentations from Abbott Australia and Nutricia Research and to serve as a member of an expert advisory committee. RV has previously received education and honorarium from the following Abbott, Nestle and Nutricia. SI has received speaker/consulting fees from Abbott, UK Dairy Council, European Milk Forum, Nestle Health Science and the Israel Milk Board.
Funding Information:
DS is supported by an Australian National Health and Medical Research Council Investigator Grant (GNT1174886). GD is supported by grants from the Australian Medical Research Future Fund (APP2005987). JAP has recently received funding from the NHMRC (APP1162867), MRFF (APP1199726), Deakin University, Amgen, Department of Health and Human Services (DHHS), and the Norman Beischer Foundation. JL is supported by a National Heart Foundation Future Leader Fellowship (ID: 102817). JZ is supported by an Australian Government Research Training Program (TRP) Scholarship. MG is supported by an NHMRC project grant (APP1099173). MS is supported by a Royal Perth Hospital Career Advancement Fellowship (CAF 130/2020), an Emerging Leader Fellowship and project grant from the Western Australian Future Health and Innovation Fund. SI has received funding from Dairy Australia, California Dairy Research Foundation, National Dairy Council, Aarhus University Hospital and Danish Dairy Research Foundation, Fonterra Co‐operative Group Ltd, Dutch Dairy Association, Dairy Council of California, Dairy Farmers of Canada, the Centre national interprofessionnel de l'economie laitiere, University of Melbourne, Austin Hospital Medical Research Foundation and Sir Edward Dunlop Medical Research Foundation. SP is supported by an NHMRC Postgraduate Scholarship, grant number 2003179. RV is supported by the NHMRC CRE 1102208 and Hospital Research Foundation.
Publisher Copyright:
© 2022 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.
PY - 2023/2
Y1 - 2023/2
N2 - BACKGROUND: Sarcopenia is an age-associated skeletal muscle condition characterized by low muscle mass, strength, and physical performance. There is no international consensus on a sarcopenia definition and no contemporaneous clinical and research guidelines specific to Australia and New Zealand. The Australian and New Zealand Society for Sarcopenia and Frailty Research (ANZSSFR) Sarcopenia Diagnosis and Management Task Force aimed to develop consensus guidelines for sarcopenia prevention, assessment, management and research, informed by evidence, consumer opinion, and expert consensus, for use by health professionals and researchers in Australia and New Zealand.METHODS: A four-phase modified Delphi process involving topic experts and informed by consumers, was undertaken between July 2020 and August 2021. Phase 1 involved a structured meeting of 29 Task Force members and a systematic literature search from which the Phase 2 online survey was developed (Qualtrics). Topic experts responded to 18 statements, using 11-point Likert scales with agreement threshold set a priori at >80%, and five multiple-choice questions. Statements with moderate agreement (70%-80%) were revised and re-introduced in Phase 3, and statements with low agreement (<70%) were rejected. In Phase 3, topic experts responded to six revised statements and three additional questions, incorporating results from a parallel Consumer Expert Delphi study. Phase 4 involved finalization of consensus statements.RESULTS: Topic experts from Australia (n = 62, 92.5%) and New Zealand (n = 5, 7.5%) with a mean ± SD age of 45.7 ± 11.8 years participated in Phase 2; 38 (56.7%) were women, 38 (56.7%) were health professionals and 27 (40.3%) were researchers/academics. In Phase 2, 15 of 18 (83.3%) statements on sarcopenia prevention, screening, assessment, management and future research were accepted with strong agreement. The strongest agreement related to encouraging a healthy lifestyle (100%) and offering tailored resistance training to people with sarcopenia (92.5%). Forty-seven experts participated in Phase 3; 5/6 (83.3%) revised statements on prevention, assessment and management were accepted with strong agreement. A majority of experts (87.9%) preferred the revised European Working Group for Sarcopenia in Older Persons (EWGSOP2) definition. Seventeen statements with strong agreement (>80%) were confirmed by the Task Force in Phase 4.CONCLUSIONS: The ANZSSFR Task Force present 17 sarcopenia management and research recommendations for use by health professionals and researchers which includes the recommendation to adopt the EWGSOP2 sarcopenia definition in Australia and New Zealand. This rigorous Delphi process that combined evidence, consumer expert opinion and topic expert consensus can inform similar initiatives in countries/regions lacking consensus on sarcopenia.
AB - BACKGROUND: Sarcopenia is an age-associated skeletal muscle condition characterized by low muscle mass, strength, and physical performance. There is no international consensus on a sarcopenia definition and no contemporaneous clinical and research guidelines specific to Australia and New Zealand. The Australian and New Zealand Society for Sarcopenia and Frailty Research (ANZSSFR) Sarcopenia Diagnosis and Management Task Force aimed to develop consensus guidelines for sarcopenia prevention, assessment, management and research, informed by evidence, consumer opinion, and expert consensus, for use by health professionals and researchers in Australia and New Zealand.METHODS: A four-phase modified Delphi process involving topic experts and informed by consumers, was undertaken between July 2020 and August 2021. Phase 1 involved a structured meeting of 29 Task Force members and a systematic literature search from which the Phase 2 online survey was developed (Qualtrics). Topic experts responded to 18 statements, using 11-point Likert scales with agreement threshold set a priori at >80%, and five multiple-choice questions. Statements with moderate agreement (70%-80%) were revised and re-introduced in Phase 3, and statements with low agreement (<70%) were rejected. In Phase 3, topic experts responded to six revised statements and three additional questions, incorporating results from a parallel Consumer Expert Delphi study. Phase 4 involved finalization of consensus statements.RESULTS: Topic experts from Australia (n = 62, 92.5%) and New Zealand (n = 5, 7.5%) with a mean ± SD age of 45.7 ± 11.8 years participated in Phase 2; 38 (56.7%) were women, 38 (56.7%) were health professionals and 27 (40.3%) were researchers/academics. In Phase 2, 15 of 18 (83.3%) statements on sarcopenia prevention, screening, assessment, management and future research were accepted with strong agreement. The strongest agreement related to encouraging a healthy lifestyle (100%) and offering tailored resistance training to people with sarcopenia (92.5%). Forty-seven experts participated in Phase 3; 5/6 (83.3%) revised statements on prevention, assessment and management were accepted with strong agreement. A majority of experts (87.9%) preferred the revised European Working Group for Sarcopenia in Older Persons (EWGSOP2) definition. Seventeen statements with strong agreement (>80%) were confirmed by the Task Force in Phase 4.CONCLUSIONS: The ANZSSFR Task Force present 17 sarcopenia management and research recommendations for use by health professionals and researchers which includes the recommendation to adopt the EWGSOP2 sarcopenia definition in Australia and New Zealand. This rigorous Delphi process that combined evidence, consumer expert opinion and topic expert consensus can inform similar initiatives in countries/regions lacking consensus on sarcopenia.
UR - http://www.scopus.com/inward/record.url?scp=85141488174&partnerID=8YFLogxK
U2 - 10.1002/jcsm.13115
DO - 10.1002/jcsm.13115
M3 - Article
C2 - 36349684
SN - 2190-5991
VL - 14
SP - 142
EP - 156
JO - Journal of Cachexia, Sarcopenia and Muscle
JF - Journal of Cachexia, Sarcopenia and Muscle
IS - 1
ER -