Abstract
Introduction/Aim:
The Bronchiectasis Health Questionnaire (BHQ) assesses health-related quality-of-life (HRQoL) in individuals with bronchiectasis. However, it has not been validated during an exacerbation, and its responsiveness to treatment has not been explored. This study aimed to establish concurrent validity of the BHQ and explore responsiveness of the BHQ to treatment in individuals experiencing an acute exacerbation of bronchiectasis.
Methods:
Adults admitted to hospital with an exacerbation of bronchiectasis completed the BHQ, Quality of Life Bronchiectasis (QoL-B) questionnaire (8 domains), Leicester Cough Questionnaire (LCQ) (3 domains) on day 2, and day of discharge from hospital. The severity of bronchiectasis was assessed using the Bronchiectasis Severity Index (BSI).
Results:
Fifty participants were recruited, 68/32 female/male ratio, with mean(SD) age 73(10) years. Most participants had severe bronchiectasis. BHQ and BSI scores were not related. There was a positive, moderate to strong correlation between BHQ score and all QoL-B domain scores on day 2 and day of discharge (r/rs = 0.45 to 0.78 day 2; 0.40 to 0.73 discharge) with the exception of Treatment Burden. There were moderate correlations between the BHQ score and LCQ total and domain scores on day 2 (r/rs = 0.51 – 0.66) and weak to moderate correlations at discharge (0.27–0.53). There was an improvement in the mean BHQ total score of 4.4 points (95% confidence interval 2.0 to 6.8; effect size = 0.55)), suggesting the BHQ was responsive to treatment from day 2 to day of discharge.
Conclusion:
The BHQ scores were moderately to strongly related to most domain scores of the QoL-B on day 2 and day of discharge from hospital. They were weakly to moderately related to total and domain scores of the LCQ. BHQ was responsive to improvement following management for an exacerbation.
The Bronchiectasis Health Questionnaire (BHQ) assesses health-related quality-of-life (HRQoL) in individuals with bronchiectasis. However, it has not been validated during an exacerbation, and its responsiveness to treatment has not been explored. This study aimed to establish concurrent validity of the BHQ and explore responsiveness of the BHQ to treatment in individuals experiencing an acute exacerbation of bronchiectasis.
Methods:
Adults admitted to hospital with an exacerbation of bronchiectasis completed the BHQ, Quality of Life Bronchiectasis (QoL-B) questionnaire (8 domains), Leicester Cough Questionnaire (LCQ) (3 domains) on day 2, and day of discharge from hospital. The severity of bronchiectasis was assessed using the Bronchiectasis Severity Index (BSI).
Results:
Fifty participants were recruited, 68/32 female/male ratio, with mean(SD) age 73(10) years. Most participants had severe bronchiectasis. BHQ and BSI scores were not related. There was a positive, moderate to strong correlation between BHQ score and all QoL-B domain scores on day 2 and day of discharge (r/rs = 0.45 to 0.78 day 2; 0.40 to 0.73 discharge) with the exception of Treatment Burden. There were moderate correlations between the BHQ score and LCQ total and domain scores on day 2 (r/rs = 0.51 – 0.66) and weak to moderate correlations at discharge (0.27–0.53). There was an improvement in the mean BHQ total score of 4.4 points (95% confidence interval 2.0 to 6.8; effect size = 0.55)), suggesting the BHQ was responsive to treatment from day 2 to day of discharge.
Conclusion:
The BHQ scores were moderately to strongly related to most domain scores of the QoL-B on day 2 and day of discharge from hospital. They were weakly to moderately related to total and domain scores of the LCQ. BHQ was responsive to improvement following management for an exacerbation.
| Original language | English |
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| Pages | 216-216 |
| Number of pages | 1 |
| DOIs | |
| Publication status | Accepted/In press - 2024 |
| Event | TSANZSRS - The Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science - Gold Coast Convention and Exhibition Centre , Gold Coast, Australia Duration: 22 Mar 2024 → 26 Mar 2024 https://tsanzsrsasm.com/ (Conference website) |
Conference
| Conference | TSANZSRS - The Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science |
|---|---|
| Country/Territory | Australia |
| City | Gold Coast |
| Period | 22/03/24 → 26/03/24 |
| Other | TSANZSRS 2024 will be held at the Gold Coast Convention and Exhibition Centre from 22nd – 26th March 2024 (ANZSRS; 23rd – 25th March and TSANZ; 23rd – 26th March) with opportunities to attend pre-conference Postgraduate Workshops on Friday 22nd March. The theme for The Thoracic Society of Australia and New Zealand 2024 Annual Scientific Meeting is a new era in health care (Innovation). The last few years have required the respiratory health community (and the entire world) to adapt and innovate in extraordinary ways. The new era in health care theme will explore these innovations and innovators in all their forms: from bench to bedside, and in the development and application of new technologies and strategies. The theme for the Australian and New Zealand Society of Respiratory Science 2024 Annual Scientific meeting is: Physiology in motion – exploring the power and science of exercise. This theme delves into the dynamic realm of exercise and its profound impact on our bodies, with a specific focus on the intricate relationship between exercise and the lungs. Exploring topics such as exercise in chronic health conditions, the disconnect of supraphysiological lung disease, and paediatric exercise testing, this gathering of respiratory exercise experts promises invaluable insights into the remarkable physiology of movement. |
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